Cradles of cellular architecture: ER nests as hubs for organelle birth

IF 8.7 1区生物学 Q1 CELL BIOLOGY

Developmental cell Pub Date : 2025-08-04 DOI:10.1016/j.devcel.2025.07.007

Dibyayan Maity, Amit S. Joshi

引用次数: 0

Abstract

In this issue of Developmental Cell, Wright et al. uncover discrete ER subdomains termed “ER nests” as sites for peroxisomes and lipid droplet (LD) biogenesis in Arabidopsis seedlings. ER nests are enriched in lipid biosynthetic enzymes, COPII components, and ER-shaping proteins that coordinate the biogenesis and contact between peroxisomes and LDs.

查看原文本刊更多论文

细胞结构的摇篮：ER巢作为细胞器诞生的枢纽

在本期的《发育细胞》中，Wright等人发现了离散的内质网亚结构域，称为“内质网巢”，是拟南芥幼苗中过氧化物酶体和脂滴（LD）生物发生的位点。内质网巢富含脂质生物合成酶、COPII成分和内质网成形蛋白，这些蛋白协调过氧化物酶体和ld之间的生物发生和接触。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Developmental cell 生物-发育生物学

CiteScore

18.90

自引率

1.70%

发文量

203

审稿时长

3-6 weeks

期刊介绍： Developmental Cell, established in 2001, is a comprehensive journal that explores a wide range of topics in cell and developmental biology. Our publication encompasses work across various disciplines within biology, with a particular emphasis on investigating the intersections between cell biology, developmental biology, and other related fields. Our primary objective is to present research conducted through a cell biological perspective, addressing the essential mechanisms governing cell function, cellular interactions, and responses to the environment. Moreover, we focus on understanding the collective behavior of cells, culminating in the formation of tissues, organs, and whole organisms, while also investigating the consequences of any malfunctions in these intricate processes.