Surgical and medical complications associated with mucormycosis in a tertiary hospital.

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Gaceta medica de Mexico Pub Date : 2025-01-01 DOI:10.24875/GMM.M25000988

Francisco J Barrera-López, Maura E Noyola-García, Natalia G Barrera-López, Alejandra Albarrán-Sánchez

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引用次数: 0

Abstract

Background: Mucormycosis is an infection caused by Mucorales. Management includes surgical treatment and antifungals.

Objective: To describe the surgical and medical complications associated with mucormycosis in a third-level hospital.

Material and methods: Records of patients with mucormycosis treated between 2019 and 2022 were collected.

Results: A total of 25 patients were obtained, 17 (68%) men and 8 (32%) women. Surgical complications occurred on admission in 16% and early in 4% of cases. The most frequent medical complications were soft tissue infection on admission (84%) and late sepsis (52%). Amphotericin B deoxycholate was used in all cases, finding hypokalemia in 20 (80%), hypomagnesemia in 18 (72%), and acute kidney injury in 15 (60%).

Conclusions: The most commonly performed surgery was surgical debridement on admission (76%). Surgical complications occurred mainly on admission (16%). The most frequent medical complications were soft tissue infection on admission (84%) and late sepsis (52%). Due to the high cost of the liposomal and lipid forms of amphotericin, the use of amphotericin B deoxycholate continues to persist in our setting, which leads to a high degree of renal toxicity and hydroelectrolytic alterations.

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三级医院毛霉菌病的外科和内科并发症。

背景：毛霉菌病是由毛霉菌引起的感染。治疗包括手术治疗和抗真菌药物。目的：了解某三级医院毛霉病的外科及内科并发症。材料与方法：收集2019 - 2022年治疗的毛霉菌病患者的记录。结果：共获得25例患者，其中男性17例（68%），女性8例（32%）。16%的病例入院时发生手术并发症，4%的病例入院早期发生手术并发症。最常见的医学并发症是入院时软组织感染（84%）和晚期败血症（52%）。所有病例均使用两性霉素B去氧胆酸盐，发现低钾血症20例（80%），低镁血症18例（72%），急性肾损伤15例（60%）。结论：最常见的手术是入院时的手术清创（76%）。手术并发症主要发生在入院时（16%）。最常见的医学并发症是入院时软组织感染（84%）和晚期败血症（52%）。由于两性霉素脂质体和脂质形式的高成本，两性霉素B脱氧胆酸盐的使用继续在我们的环境中持续存在，这导致了高度的肾毒性和水电解质改变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gaceta medica de Mexico 医学-医学：内科

CiteScore

1.00

自引率

0.00%

发文量

216

审稿时长

6-12 weeks

期刊介绍： Gaceta Médica de México México is the official scientific journal of the Academia Nacional de Medicina de México, A.C. Its goal is to contribute to health professionals by publishing the most relevant progress both in research and clinical practice. Gaceta Médica de México is a bimonthly peer reviewed journal, published both in paper and online in open access, both in Spanish and English. It has a brilliant editorial board formed by national and international experts.