68Ga-PSMA PET/CT in a case of recurrent Glioblastoma.

Abstract

Glioblastoma multiforme (GBM) is a high-grade brain tumor with a high recurrence rate. We present the case of a 57-year-old man with left frontal lobe GBM who was operated on and received radiation therapy in June 2023 and was referred for ⁶⁸Ga-PSMA 11 PET/CT with a clinical suspicion of recurrence. The scan showed intense tracer uptake in the left frontal lobe lesion with severe edema, which was consistent with recurrence. Our case underscores the role of ⁶⁸Ga PSMA 11 PET/CT imaging of suspected glioblastoma recurrence which is the initial step in GBM theranostics with PSMA.