Rare systemic skin hyperpigmentation associated with osimertinib: A case report.

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Le Li, Lifang Yang, Guanglei Xu, Zhouqian Jiang
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引用次数: 0

Abstract

A patient with advanced small cell lung cancer presented with systemic skin pigmentation, a rare and severe skin adverse reaction during treatment with osimertinib. Osimertinib-induced hyperpigmentation is rarely reported, According to the patient's condition, adverse drug reactions, and drug efficacy, osimertinib was the urgently needed treatment regimen, and 80 mg of osimertinib was continued. Therefore, we hope this case can provide experience for clinicians to identify adverse reactions of the drug and ensure the safety of patients.

罕见的系统性皮肤色素沉着与奥希替尼相关:1例报告。
一名晚期小细胞肺癌患者在奥西替尼治疗期间出现全身皮肤色素沉着,这是一种罕见且严重的皮肤不良反应。奥西替尼引起的色素沉着很少报道,根据患者的病情、药物不良反应和药物疗效,奥西替尼是迫切需要的治疗方案,并继续给予80mg奥西替尼。因此,我们希望本案例能为临床医生识别药物不良反应,保障患者安全提供经验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.70
自引率
12.50%
发文量
116
审稿时长
4-8 weeks
期刊介绍: The International Journal of Clinical Pharmacology and Therapeutics appears monthly and publishes manuscripts containing original material with emphasis on the following topics: Clinical trials, Pharmacoepidemiology - Pharmacovigilance, Pharmacodynamics, Drug disposition and Pharmacokinetics, Quality assurance, Pharmacogenetics, Biotechnological drugs such as cytokines and recombinant antibiotics. Case reports on adverse reactions are also of interest.
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