Tooth Graft and Platelet-Rich Fibrin Mixture for Oral Bone Reconstruction and Preservation: A Scoping Review

IF 2.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research Pub Date : 2025-07-31 DOI:10.1002/cre2.70160

Mina Shekarian, Fateme Aghajani, Zahra Sadat Mohajer Hejazi, Pedram Iranmanesh, Bahamin Mousa Akbari-Bezenjani, Abbasali Khademi

{"title":"Tooth Graft and Platelet-Rich Fibrin Mixture for Oral Bone Reconstruction and Preservation: A Scoping Review","authors":"Mina Shekarian, Fateme Aghajani, Zahra Sadat Mohajer Hejazi, Pedram Iranmanesh, Bahamin Mousa Akbari-Bezenjani, Abbasali Khademi","doi":"10.1002/cre2.70160","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Aim</h3>\n \n <p>This scoping review aimed to evaluate effectiveness of using tooth graft (TG) mixture with platelet-rich fibrin (PRF), examining their roles in oral bone reconstruction and preservation, and evaluating the clinical and histopathological outcomes associated with this approach.</p>\n </section>\n \n <section>\n \n <h3> Material and Methods</h3>\n \n <p>Articles were searched in Scopus, Medline, Web of Science, ProQuest, and Google Scholar up to November 2024. The search was guided by the PCC framework: Population: alveolar bone and calvaria bone defects; Concept: the use of a TG mixture with PRF as a bone graft material; Context: clinical and histopathological outcomes of oral bone reconstruction and preservation. Two independent researchers carried out the screening, study selection, and data extraction processes.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Use of the PRF and TG mixture for socket preservation is superior to using each of these biomaterials individually. However, in the context of bone reconstruction, although all studies confirm new bone formation, the superiority of this mixture over the separate use of each biomaterial remains uncertain. Additionally, all studies confirm the increase in bone density and new bone formation aimed at implant placement.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>The majority of studies have reported that the PRF and TG mixture enhances both the quality and quantity of bone.</p>\n </section>\n </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 4","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70160","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Dental Research","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cre2.70160","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Aim

This scoping review aimed to evaluate effectiveness of using tooth graft (TG) mixture with platelet-rich fibrin (PRF), examining their roles in oral bone reconstruction and preservation, and evaluating the clinical and histopathological outcomes associated with this approach.

Material and Methods

Articles were searched in Scopus, Medline, Web of Science, ProQuest, and Google Scholar up to November 2024. The search was guided by the PCC framework: Population: alveolar bone and calvaria bone defects; Concept: the use of a TG mixture with PRF as a bone graft material; Context: clinical and histopathological outcomes of oral bone reconstruction and preservation. Two independent researchers carried out the screening, study selection, and data extraction processes.

Results

Use of the PRF and TG mixture for socket preservation is superior to using each of these biomaterials individually. However, in the context of bone reconstruction, although all studies confirm new bone formation, the superiority of this mixture over the separate use of each biomaterial remains uncertain. Additionally, all studies confirm the increase in bone density and new bone formation aimed at implant placement.

Conclusion

The majority of studies have reported that the PRF and TG mixture enhances both the quality and quantity of bone.

Abstract Image

查看原文本刊更多论文

牙移植物和富血小板纤维蛋白混合物用于口腔骨重建和保存：范围综述

目的本综述旨在评估富血小板纤维蛋白（PRF）混合牙移植物（TG）的有效性，研究其在口腔骨重建和保存中的作用，并评估与该方法相关的临床和组织病理学结果。截止到2024年11月，在Scopus， Medline, Web of Science， ProQuest和谷歌Scholar中检索了文章。研究遵循PCC框架：人群：牙槽骨和颅骨骨缺损；概念：使用TG混合PRF作为骨移植材料；背景：口腔骨重建和保存的临床和组织病理学结果。两名独立研究人员进行了筛选、研究选择和数据提取过程。结果使用PRF和TG混合材料保存牙槽优于单独使用每种生物材料。然而，在骨重建的背景下，尽管所有的研究都证实了新骨的形成，但这种混合物比单独使用每种生物材料的优势仍然不确定。此外，所有的研究都证实了增加骨密度和新骨形成的目的是种植体放置。结论PRF和TG的混合物可以提高骨的质量和数量，这是大多数研究报道的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical and Experimental Dental Research DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.30

自引率

5.60%

发文量

165

审稿时长

26 weeks

期刊介绍： Clinical and Experimental Dental Research aims to provide open access peer-reviewed publications of high scientific quality representing original clinical, diagnostic or experimental work within all disciplines and fields of oral medicine and dentistry. The scope of Clinical and Experimental Dental Research comprises original research material on the anatomy, physiology and pathology of oro-facial, oro-pharyngeal and maxillofacial tissues, and functions and dysfunctions within the stomatognathic system, and the epidemiology, aetiology, prevention, diagnosis, prognosis and therapy of diseases and conditions that have an effect on the homeostasis of the mouth, jaws, and closely associated structures, as well as the healing and regeneration and the clinical aspects of replacement of hard and soft tissues with biomaterials, and the rehabilitation of stomatognathic functions. Studies that bring new knowledge on how to advance health on the individual or public health levels, including interactions between oral and general health and ill-health are welcome.