Development of a Cutaneous Horn on a Lower Extremity with Granuloma Annulare: A Rare Co-Occurrence.

IF 2.2 4区 医学 Q3 DERMATOLOGY
Clinical, Cosmetic and Investigational Dermatology Pub Date : 2025-07-19 eCollection Date: 2025-01-01 DOI:10.2147/CCID.S520386
Xiaolin Bu, Liwei Feng, Jing Guo, Rongzhu Yu, Xinling Bi
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引用次数: 0

Abstract

A 65-year-old Asian male presented with a circular skin lesion on the flexor aspect of the right calf that first appeared at age 13 and gradually expanded peripherally. Six months prior to presentation, a dark brown, horn-like keratotic lesion with a hard texture emerged on the annular lesion, growing progressively without pain or pruritus. The cutaneous horn was surgically excised, and the annular lesion underwent biopsy. Pathological findings revealed abundant mucin in dermal collagen, dense histiocyte infiltration, and focal mild collagen degeneration, confirming a diagnosis of granuloma annulare complicated by a cutaneous horn.

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下肢皮肤角与环形肉芽肿的发展:罕见的共同发生。
65岁亚洲男性,右小腿屈肌侧出现圆形皮肤病变,首次出现于13岁,并逐渐向周围扩展。在发病前6个月,环状病变上出现深棕色角状角膜病变,质地坚硬,逐渐生长,无疼痛或瘙痒。手术切除皮角,并对环形病变进行活检。病理结果显示真皮胶原蛋白中有丰富的粘蛋白,致密的组织细胞浸润,局灶性轻度胶原变性,确认诊断为环形肉芽肿合并皮角。
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来源期刊
CiteScore
2.80
自引率
4.30%
发文量
353
审稿时长
16 weeks
期刊介绍: Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.
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