Nutritional content and renoprotective potential of miracle tree (Moringa oleifera).

Biotechnologia Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI:10.5114/bta/204529

Vibhuti Sharma, Gaytri Mahajan, Reena Gupta

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Abstract

Kidney disease is a significant global health issue. This review explores the causes of renal illness, the therapeutic properties of the angiosperm Moringa oleifera, and its potential effectiveness in kidney disease management. In chronic kidney disease, inflammatory processes and immune cell activation lead to excessive free radical production, resulting in oxidative stress due to diminished antioxidant capacity. M. oleifera possesses diverse health benefits, particularly its ability to enhance antioxidant defenses. Extracts from its stem, seed, and leaf powders have been shown to increase the activity of key antioxidant enzymes, including glutathione, superoxide dismutase, and catalase. Additionally, M. oleifera modulates inflammation by reducing the activity of TNF-α, COX-2, and other pro-inflammatory cytokines. This review provides insights into the pharmacological and therapeutic potential of M. oleifera, highlighting its promise in the development of novel treatments for kidney-related disorders. Moreover, its bioactive compounds may contribute to renal tissue regeneration and protection against nephrotoxic agents.

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神奇树辣木的营养成分及肾保护潜力。

肾脏疾病是一个重大的全球健康问题。本文综述了被子植物辣木（Moringa oleifera）的病因、治疗特性及其在肾脏疾病治疗中的潜在疗效。在慢性肾脏疾病中，炎症过程和免疫细胞激活导致过多的自由基产生，由于抗氧化能力降低而导致氧化应激。油葵具有多种健康益处，特别是其增强抗氧化防御的能力。从其茎、种子和叶粉末中提取的提取物已被证明可以增加关键抗氧化酶的活性，包括谷胱甘肽、超氧化物歧化酶和过氧化氢酶。此外，M. oleifera通过降低TNF-α， COX-2和其他促炎细胞因子的活性来调节炎症。这篇综述提供了对油橄榄的药理和治疗潜力的见解，强调了它在开发肾脏相关疾病的新疗法方面的前景。此外，其生物活性化合物可能有助于肾组织再生和对肾毒性药物的保护。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biotechnologia

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