Colorimetric ALP detection with a ligand-exchanged Au8 cluster†

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-08-04 DOI:10.1039/d5cc02136g

Jingjing Yang , Qing You , Qian Wang , Hongliang Zhao , Yu Cheng , Ming Yao , Junchi Ruan , Yan Zhao , Man-Bo Li , Zhikun Wu

引用次数: 0

Abstract

An atomically precise Au₈ nanocluster (dppm/dppp) synthesized via ligand exchange exhibits oxidase-like activity. Alkaline phosphatase (ALP) quenches O₂˙⁻, enabling sensitive and specific colorimetric detection and demonstrating diagnostic potential.

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配体交换Au的比色法ALP检测

通过配体交换合成的原子精密Au₈纳米团簇（dppm/dppp）具有类似氧化酶的活性。碱性磷酸酶（ALP）能淬灭O₂•毒血症，使比色法检测变得敏感和特异，并显示出诊断的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.