Viromics approaches for the study of viral diversity and ecology in microbiomes

IF 52 1区 生物学 Q1 GENETICS & HEREDITY
Simon Roux, Clement Coclet
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引用次数: 0

Abstract

Viruses are found across all ecosystems and infect every type of organism on Earth. Traditional culture-based methods have proven insufficient to explore this viral diversity at scale, driving the development of viromics, the sequence-based analysis of uncultivated viruses. Viromics approaches have been particularly useful for studying viruses of microorganisms, which can act as crucial regulators of microbiomes across ecosystems. They have already revealed the broad geographic distribution of viral communities and are progressively uncovering the expansive genetic and functional diversity of the global virome. Moving forward, large-scale viral ecogenomics studies combined with new experimental and computational approaches to identify virus activity and host interactions will enable a more complete characterization of global viral diversity and its effects.

Abstract Image

微生物组中病毒多样性和生态学研究的病毒组学方法
病毒存在于所有生态系统中,感染地球上所有类型的生物。传统的基于培养的方法已被证明不足以大规模探索这种病毒多样性,这推动了病毒组学的发展,即对未培养的病毒进行基于序列的分析。病毒组学方法在研究微生物病毒方面特别有用,它们可以作为生态系统中微生物组的关键调节者。他们已经揭示了病毒群落的广泛地理分布,并逐步揭示了全球病毒群的广泛遗传和功能多样性。展望未来,大规模的病毒生态基因组学研究结合新的实验和计算方法来识别病毒活性和宿主相互作用,将使全球病毒多样性及其影响的更完整表征成为可能。
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来源期刊
Nature Reviews Genetics
Nature Reviews Genetics 生物-遗传学
CiteScore
57.40
自引率
0.50%
发文量
113
审稿时长
6-12 weeks
期刊介绍: At Nature Reviews Genetics, our goal is to be the leading source of reviews and commentaries for the scientific communities we serve. We are dedicated to publishing authoritative articles that are easily accessible to our readers. We believe in enhancing our articles with clear and understandable figures, tables, and other display items. Our aim is to provide an unparalleled service to authors, referees, and readers, and we are committed to maximizing the usefulness and impact of each article we publish. Within our journal, we publish a range of content including Research Highlights, Comments, Reviews, and Perspectives that are relevant to geneticists and genomicists. With our broad scope, we ensure that the articles we publish reach the widest possible audience. As part of the Nature Reviews portfolio of journals, we strive to uphold the high standards and reputation associated with this esteemed collection of publications.
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