{"title":"The impact of Low-Anterior Resection Syndrome (LARS) on the Quality of Life in Rectal Cancer Survivors: a Narrative Review.","authors":"Floris Stanculea, Claudiu-Octavian Ungureanu, Daniela Roca, Octav Ginghina, Raul Mihailov, Florin Grama, Niculae Iordache","doi":"10.26574/maedica.2025.20.1.56","DOIUrl":null,"url":null,"abstract":"<p><p>Low anterior rectal cancer is based on oncological radicality and recurrence rates, which translate to survival. Rectal dysfunction occurred in at least one-quarter of patients. This dysfunction is a myriad of symptoms referred to as low anterior resection syndrome (LARS). In this review, we analyzed the definitions, risk factors and pathophysiological mechanisms of LARS. A better understanding of this syndrome can lead to improved prevention and treatment of LARS.</p>","PeriodicalId":74094,"journal":{"name":"Maedica","volume":"20 1","pages":"56-64"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12123494/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Maedica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26574/maedica.2025.20.1.56","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Low anterior rectal cancer is based on oncological radicality and recurrence rates, which translate to survival. Rectal dysfunction occurred in at least one-quarter of patients. This dysfunction is a myriad of symptoms referred to as low anterior resection syndrome (LARS). In this review, we analyzed the definitions, risk factors and pathophysiological mechanisms of LARS. A better understanding of this syndrome can lead to improved prevention and treatment of LARS.
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