Linear IgA Vasculitis: Cutaneous Small-Vessel Leukocytoclastic Vasculitis, in Association With Linear IgA Disease-Type Immunoreactant Deposition Along Epidermal Basement Membrane Zone

IF 1.1 4区医学 Q3 DERMATOLOGY

Journal of Cutaneous Pathology Pub Date : 2025-07-13 DOI:10.1111/cup.14843

Michael Murphy, Timothy Klufas, Joseph Beauchemin, Shannon Hanggodo, Albert Zhou

引用次数: 0

Abstract

We present a 69-year-old male with overlapping clinical-histopathological-immunological features of cutaneous leukocytoclastic vasculitis (LCV) and linear IgA disease (LAD). The patient's disease was considered idiopathic, with a possible underlying infectious trigger/etiology. The term “linear IgA vasculitis” is proposed to describe those patients with rarely reported combined LCV-LAD findings, and includes idiopathic, drug-induced, and paraneoplastic causes.

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线性IgA血管炎：皮肤小血管白细胞破裂性血管炎，与线性IgA病型免疫反应物沿表皮基底膜区沉积有关。

我们报告一位69岁男性患者，其临床、组织病理学和免疫学特征与皮肤白细胞破坏性血管炎（LCV）和线性IgA疾病（LAD）重叠。患者的疾病被认为是特发性的，可能是潜在的感染触发/病因。“线性IgA血管炎”一词被用来描述那些很少报道LCV-LAD合并发现的患者，包括特发性、药物诱导和副肿瘤原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Cutaneous Pathology 医学-病理学

CiteScore

3.20

自引率

5.90%

发文量

174

审稿时长

3-8 weeks

期刊介绍： Journal of Cutaneous Pathology publishes manuscripts broadly relevant to diseases of the skin and mucosae, with the aims of advancing scientific knowledge regarding dermatopathology and enhancing the communication between clinical practitioners and research scientists. Original scientific manuscripts on diagnostic and experimental cutaneous pathology are especially desirable. Timely, pertinent review articles also will be given high priority. Manuscripts based on light, fluorescence, and electron microscopy, histochemistry, immunology, molecular biology, and genetics, as well as allied sciences, are all welcome, provided their principal focus is on cutaneous pathology. Publication time will be kept as short as possible, ensuring that articles will be quickly available to all interested in this speciality.