Risk factors for adjacent vertebral fracture after kyphoplasty or percutaneous vertebroplasty in osteoporotic vertebral systematic review and meta-analysis compression fractures.

IF 2.6 3区医学 Q2 CLINICAL NEUROLOGY

European Spine Journal Pub Date : 2025-07-14 DOI:10.1007/s00586-025-09111-5

Lei He, Wei Li, Xingpeng Zhai, Zhiwei Li

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引用次数: 0

Abstract

Objective: To systematically evaluate the risk factors of adjacent vertebral re-fracture after percutaneous vertebroplasty and percutaneous kyphoplasty for osteoporotic vertebral compression fractures.

Methods: PubMed, Embase, The Cochrane Library, Web of Science, CNKI, Wanfang, VIP, CBM and other databases were searched by computer to collect case-control studies on adjacent vertebral re-fracture after vertebroplasty for osteoporotic vertebral compression fractures. The retrieval time was from the establishment of the database to July 17,2024. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Meta-analysis was performed using Stata 17.0 software.

Results: A total of 26 articles were included, including 7604 patients. The results of Meta-analysis showed that postoperative bone cement leakage, excessive recovery rate of vertebral height, too little or too much bone cement injection, low bone mineral density, high recovery rate of anterior vertebral height, no anti-osteoporosis treatment after operation, too many injured vertebrae, previous history of fracture, older age and female patients were risk factors for AVCF. High level of bone cement distribution index, physical exercise after operation and low BMI index are protective factors for AVCF.

Conclusion: There are many risk factors for adjacent vertebral re-fracture after vertebroplasty for osteoporotic vertebral compression fractures. Medical staff should make comprehensive assessment, prevention and intervention.

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骨质疏松性椎体压缩性骨折后凸成形术或经皮椎体成形术后邻近椎体骨折的危险因素。

目的：系统评价骨质疏松性椎体压缩性骨折经皮椎体成形术和经皮椎体后凸成形术后相邻椎体再骨折的危险因素。方法：计算机检索PubMed、Embase、The Cochrane Library、Web of Science、CNKI、万方、VIP、CBM等数据库，收集骨质疏松性椎体压缩性骨折椎体成形术后相邻椎体再骨折的病例对照研究。检索时间为数据库建立至2024年7月17日。两名审稿人独立筛选文献、提取数据并评估纳入研究的偏倚风险。采用Stata 17.0软件进行meta分析。结果：共纳入文献26篇，患者7604例。meta分析结果显示，术后骨水泥渗漏、椎体高度恢复率过高、骨水泥注射量过少或过多、骨密度低、前段椎体高度恢复率高、术后未进行抗骨质疏松治疗、损伤椎体过多、既往有骨折史、年龄较大及女性患者是AVCF发生的危险因素。高水平骨水泥分布指数、术后体育锻炼和低BMI指数是AVCF的保护因素。结论：骨质疏松性椎体压缩性骨折椎体成形术后邻近椎体再骨折的危险因素较多。医务人员应综合评估、预防和干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Spine Journal 医学-临床神经学

CiteScore

4.80

自引率

10.70%

发文量

373

审稿时长

2-4 weeks

期刊介绍： "European Spine Journal" is a publication founded in response to the increasing trend toward specialization in spinal surgery and spinal pathology in general. The Journal is devoted to all spine related disciplines, including functional and surgical anatomy of the spine, biomechanics and pathophysiology, diagnostic procedures, and neurology, surgery and outcomes. The aim of "European Spine Journal" is to support the further development of highly innovative spine treatments including but not restricted to surgery and to provide an integrated and balanced view of diagnostic, research and treatment procedures as well as outcomes that will enhance effective collaboration among specialists worldwide. The “European Spine Journal” also participates in education by means of videos, interactive meetings and the endorsement of educative efforts. Official publication of EUROSPINE, The Spine Society of Europe