Takeuchi repair for anomalous origin of the left coronary artery from the pulmonary artery: functional recovery and late complications in an 18-patient cohort.

IF 0.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Osman Nuri Tuncer, Mahsati Akhundova, Ertürk Levent, Yüksel Atay
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引用次数: 0

Abstract

Background: The Takeuchi procedure remains an important surgical option for treating anomalous origin of the left coronary artery from the pulmonary artery, particularly in cases where direct coronary reimplantation is not feasible. However, long-term outcome data in paediatric patients are limited.

Methods: We retrospectively reviewed 18 paediatric patients who underwent Takeuchi repair between 2007 and 2023. Clinical characteristics, echocardiographic data, and outcomes-including survival, ventricular function, mitral regurgitation, and reintervention-were analysed. Kaplan-Meier analysis was used to assess survival and freedom from reintervention, and paired comparisons were evaluated using the Wilcoxon signed-rank test.

Results: The median age at surgery was 6 months (range: 25 days to 12 years). Preoperative left ventricular ejection fraction was significantly depressed (median 23.5%), and mitral regurgitation was present in all patients. There were two early deaths (11.1%), both in patients with severe heart failure. No late mortality was observed during a maximum follow-up of 10.9 years. All survivors achieved New York Heart Association class I status. Left ventricular ejection fraction improved significantly postoperatively (p < 0.0001), and mitral regurgitation grade also decreased significantly (p < 0.001), with 94.4% showing only mild residual mitral regurgitation. Reintervention occurred in three patients (16.7%) for pulmonary artery stenosis or baffle leak. Freedom from reintervention at 10.9 years was 66.7%.

Conclusion: The Takeuchi procedure offers excellent survival and functional recovery in paediatric anomalous origin of the left coronary artery from the pulmonary artery patients when coronary translocation is not feasible. Although late complications such as pulmonary artery stenosis or baffle leak can occur, outcomes remain favourable with appropriate follow-up.

左冠状动脉异常起源地的Takeuchi修复:18例患者的功能恢复和晚期并发症
背景:Takeuchi手术仍然是治疗左冠状动脉起源于肺动脉异常的重要手术选择,特别是在直接冠状动脉再植入术不可行的情况下。然而,儿科患者的长期结果数据有限。方法:我们回顾性分析了2007年至2023年间接受Takeuchi修复术的18例儿科患者。分析了临床特征、超声心动图数据和结果,包括生存、心室功能、二尖瓣反流和再干预。Kaplan-Meier分析用于评估生存率和免于再干预,使用Wilcoxon符号秩检验评估配对比较。结果:手术时中位年龄为6个月(范围:25天至12岁)。术前左心室射血分数明显降低(中位23.5%),所有患者均出现二尖瓣返流。有2例早期死亡(11.1%),均为严重心力衰竭患者。在最长10.9年的随访期间未观察到晚期死亡。所有幸存者都达到了纽约心脏协会的I级身份。术后左室射血分数明显改善(p < 0.0001),二尖瓣返流等级也显著降低(p < 0.001), 94.4%的患者仅出现轻度二尖瓣返流残留。3例(16.7%)患者因肺动脉狭窄或折流管泄漏再次介入治疗。10.9年无再干预率为66.7%。结论:对于不能进行冠状动脉易位的小儿左冠状动脉异常起源地肺动脉的患者,Takeuchi手术具有良好的生存率和功能恢复。虽然后期并发症,如肺动脉狭窄或挡板泄漏可以发生,结果仍然是良好的适当随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cardiology in the Young
Cardiology in the Young 医学-小儿科
CiteScore
1.70
自引率
10.00%
发文量
715
审稿时长
4-8 weeks
期刊介绍: Cardiology in the Young is devoted to cardiovascular issues affecting the young, and the older patient suffering the sequels of congenital heart disease, or other cardiac diseases acquired in childhood. The journal serves the interests of all professionals concerned with these topics. By design, the journal is international and multidisciplinary in its approach, and members of the editorial board take an active role in the its mission, helping to make it the essential journal in paediatric cardiology. All aspects of paediatric cardiology are covered within the journal. The content includes original articles, brief reports, editorials, reviews, and papers devoted to continuing professional development.
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