Can obesity pharmacotherapy be used to manage male infertility?

IF 40 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Amy E. Morrison, Dimitris Papamargaritis, Channa N. Jayasena, Neelam Potdar, Thomas Yates, Gregory J. H. Biddle, Malak Hamza, Melanie J. Davies, Narendra L. Reddy
{"title":"Can obesity pharmacotherapy be used to manage male infertility?","authors":"Amy E. Morrison, Dimitris Papamargaritis, Channa N. Jayasena, Neelam Potdar, Thomas Yates, Gregory J. H. Biddle, Malak Hamza, Melanie J. Davies, Narendra L. Reddy","doi":"10.1038/s41574-025-01151-7","DOIUrl":null,"url":null,"abstract":"Obesity-related subfertility is an increasingly recognized concern. Pharmacotherapies (particularly glucagon-like peptide 1 receptor agonists and combination therapies), alongside lifestyle intervention, enable meaningful and sustainable weight loss in people with and without type 2 diabetes mellitus. Weight loss can benefit sperm parameters, but the optimal amount and rate of weight loss requires further study.","PeriodicalId":18916,"journal":{"name":"Nature Reviews Endocrinology","volume":"38 1","pages":""},"PeriodicalIF":40.0000,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Endocrinology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41574-025-01151-7","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0

Abstract

Obesity-related subfertility is an increasingly recognized concern. Pharmacotherapies (particularly glucagon-like peptide 1 receptor agonists and combination therapies), alongside lifestyle intervention, enable meaningful and sustainable weight loss in people with and without type 2 diabetes mellitus. Weight loss can benefit sperm parameters, but the optimal amount and rate of weight loss requires further study.

Abstract Image

肥胖药物治疗可以用于治疗男性不育症吗?
与肥胖相关的生育能力低下越来越受到关注。药物治疗(特别是胰高血糖素样肽受体激动剂和联合治疗),加上生活方式干预,使2型糖尿病患者和非2型糖尿病患者的体重减轻有意义和可持续。减肥可以使精子参数受益,但减肥的最佳量和速度需要进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Nature Reviews Endocrinology
Nature Reviews Endocrinology 医学-内分泌学与代谢
CiteScore
42.00
自引率
0.70%
发文量
158
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Endocrinology aspires to be the foremost platform for reviews and commentaries catering to the scientific communities it serves. The journal aims to publish articles characterized by authority, accessibility, and clarity, enhanced with easily understandable figures, tables, and other visual aids. The goal is to offer an unparalleled service to authors, referees, and readers, striving to maximize the usefulness and impact of each article. Nature Reviews Endocrinology publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians in the fields of endocrinology and metabolism. Its broad scope ensures that the work it publishes reaches the widest possible audience.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信