Spotlight on Alzheimer's disease and related dementias research in East Asia

IF 13 1区医学 Q1 CLINICAL NEUROLOGY

Alzheimer's & Dementia Pub Date : 2025-07-10 DOI:10.1002/alz.70479

Weidong Le, Lu Shen, Tengfei Guo, Fang Xie

引用次数: 0

Abstract

With a burgeoning dementia burden driven by unique demographic, genetic, and socioeconomic factors of East Asia, the region has made significant investments in understanding disease mechanisms, developing biomarkers, and exploring therapeutic approaches. This collection highlights the current landscape of Alzheimer's disease and related dementias research in East Asia, including region-specific epidemiological insights, advances in plasma biomarkers and neuroimaging, and innovative diagnostic and treatment strategies. Despite progress, challenges such as limited access to advanced imaging, cultural barriers to autopsy, and disparities in healthcare persist.

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关注东亚地区阿尔茨海默病及相关痴呆症的研究

由于东亚独特的人口、遗传和社会经济因素导致痴呆症负担迅速增加，该地区在了解疾病机制、开发生物标志物和探索治疗方法方面进行了大量投资。该收藏突出了东亚阿尔茨海默病和相关痴呆症研究的现状，包括特定区域的流行病学见解，血浆生物标志物和神经影像学的进展，以及创新的诊断和治疗策略。尽管取得了进展，但诸如获得先进成像的机会有限、尸检的文化障碍以及医疗保健方面的差异等挑战仍然存在。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Alzheimer's & Dementia 医学-临床神经学

CiteScore

14.50

自引率

5.00%

发文量

299

审稿时长

3 months

期刊介绍： Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.