Early Vitrectomy in Endophthalmitis: Visual Outcomes and Complication Rates.

IF 2.6 3区医学 Q2 OPHTHALMOLOGY

Ophthalmology and Therapy Pub Date : 2025-08-01 Epub Date: 2025-07-09 DOI:10.1007/s40123-025-01196-x

Julian W Sromicki, Marc Stahel, Robert A Blum, Katrin A Rudolph, Daniel Barthelmes

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引用次数: 0

Abstract

Introduction: This study examined visual outcomes and complication rates after early pars plana vitrectomy (PPV) in eyes with endophthalmitis.

Methods: The study was designed as a single-center, retrospective, observational database study. A total of 92 eyes treated with early PPV for endophthalmitis at the University Hospital Zurich between 2006 and 2016 were included. Endophthalmitis cases following cataract surgery (CAT, n = 44), intravitreal injection (IVI, n = 12), trabeculectomy (TRAB, n = 6), and Others (e.g., trauma or endogenous, n = 30) were assessed. Visual acuity (VA) and intraocular pressure (IOP) from prior to endophthalmitis to 12 months after PPV were analyzed. Secondary outcomes included complications following the procedure.

Results: CAT and IVI groups showed good visual outcomes. Final VA in CAT and IVI groups was not statistically different to prior to endophthalmitis (CAT p = 0.840, IVI p = 0.933). In the CAT group, 78.9% of eyes with a starting VA of > light perception achieved ≥ 20/40 final VA. The highest rate of patients with at least one complication was observed in TRAB (100%), followed by Others (63.3%), IVI (50.0%), and CAT groups (40.9%).

Conclusion: Early PPV may be beneficial in endophthalmitis following cataract surgery and intravitreal injection, regardless of initial VA.

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眼内炎的早期玻璃体切除术：视力结果和并发症发生率。

摘要：本研究探讨了眼内炎患者早期玻璃体切割术后的视力结果和并发症发生率。方法：本研究采用单中心、回顾性、观察性数据库研究。在2006年至2016年期间，共有92只眼睛在苏黎世大学医院接受了早期PPV治疗眼内炎。评估白内障手术后眼内炎（CAT, n = 44）、玻璃体内注射（IVI, n = 12）、小梁切除术（TRAB, n = 6）和其他（如外伤或内源性，n = 30）病例。分析眼内炎前至PPV后12个月的视力（VA）和眼内压（IOP）。次要结果包括手术后的并发症。结果：CAT组和IVI组视觉效果良好。CAT组和IVI组的最终VA与眼内炎前比较无统计学差异（CAT p = 0.840, IVI p = 0.933）。在CAT组中，78.9%的起始视障率为>的眼睛达到≥20/40的最终视障率，至少有一种并发症的患者比例最高的是TRAB组（100%），其次是其他组（63.3%），IVI组（50.0%）和CAT组（40.9%）。结论：早期PPV可能对白内障手术和玻璃体内注射后的眼内炎有益，与初始VA无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmology and Therapy OPHTHALMOLOGY-

CiteScore

4.20

自引率

3.00%

发文量

157

审稿时长

6 weeks

期刊介绍： Aims and Scope Ophthalmology and Therapy is an international, open access, peer-reviewed (single-blind), and rapid publication journal. The scope of the journal is broad and will consider all scientifically sound research from preclinical, clinical (all phases), observational, real-world, and health outcomes research around the use of ophthalmological therapies, devices, and surgical techniques. The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports/series, trial protocols and short communications such as commentaries and editorials. Ophthalmology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. 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