Sergio G. Lopez, Sebastian Samwald, Sally Jones, Christine Faulkner
{"title":"Response to Adler and Parmryd","authors":"Sergio G. Lopez, Sebastian Samwald, Sally Jones, Christine Faulkner","doi":"10.1111/jmi.13428","DOIUrl":null,"url":null,"abstract":"<p>The Pearson Correlation Coefficient can be calculated using three different criteria for pixel selection. These criteria carry different implications for interpretation of the metric. Different image analysis tools use these different criteria, and it is important that users know which criteria they have used. We maintain that this is important information for the community to consider and that we accurately addressed this topic. Adler and Parmryd have identified a flaw in our analysis in Figure 2 and here we explain how this came about and provide a correction. Alder and Parmryd's letter maligns our intent and competency – we refute all accusations and we object to the use of <i>ad hominem</i> arguments in scientific discourse.</p>","PeriodicalId":16484,"journal":{"name":"Journal of microscopy","volume":"299 2","pages":"99-103"},"PeriodicalIF":1.9000,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of microscopy","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jmi.13428","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MICROSCOPY","Score":null,"Total":0}
引用次数: 0
Abstract
The Pearson Correlation Coefficient can be calculated using three different criteria for pixel selection. These criteria carry different implications for interpretation of the metric. Different image analysis tools use these different criteria, and it is important that users know which criteria they have used. We maintain that this is important information for the community to consider and that we accurately addressed this topic. Adler and Parmryd have identified a flaw in our analysis in Figure 2 and here we explain how this came about and provide a correction. Alder and Parmryd's letter maligns our intent and competency – we refute all accusations and we object to the use of ad hominem arguments in scientific discourse.
期刊介绍:
The Journal of Microscopy is the oldest journal dedicated to the science of microscopy and the only peer-reviewed publication of the Royal Microscopical Society. It publishes papers that report on the very latest developments in microscopy such as advances in microscopy techniques or novel areas of application. The Journal does not seek to publish routine applications of microscopy or specimen preparation even though the submission may otherwise have a high scientific merit.
The scope covers research in the physical and biological sciences and covers imaging methods using light, electrons, X-rays and other radiations as well as atomic force and near field techniques. Interdisciplinary research is welcome. Papers pertaining to microscopy are also welcomed on optical theory, spectroscopy, novel specimen preparation and manipulation methods and image recording, processing and analysis including dynamic analysis of living specimens.
Publication types include full papers, hot topic fast tracked communications and review articles. Authors considering submitting a review article should contact the editorial office first.