An Open-Source Browser-Based Nonlinear Model Predictive Controller for Type 1 Diabetes

Q3 Engineering

IFAC-PapersOnLine Pub Date : 2025-01-01 DOI:10.1016/j.ifacol.2025.06.025

Lara Hauser , John Bagterp Jørgensen , Heiko Peuscher

引用次数: 0

Abstract

We provide an open-source implementation of the NMPC algorithm for closed-loop insulin therapy presented by Hovorka et. al. in the seminal paper from 2004. An extended Kalman filter is added as observer, since specifics on state estimation have been omitted in the original paper. The controller is now part of the TypeScript-based closed-loop diabetes simulator LT1, which also comprises a library of models describing CGM sensors, infusion pumps, and patient physiology. The controller can thus be extensively tested in various closed-loop configurations. Also, the graphical user interface enables its integration in educational tools.

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基于开源浏览器的1型糖尿病非线性模型预测控制器

我们为Hovorka等人在2004年的开创性论文中提出的闭环胰岛素治疗的NMPC算法提供了一个开源实现。由于原论文中省略了状态估计的细节，因此增加了扩展卡尔曼滤波器作为观测器。该控制器现在是基于typescript的闭环糖尿病模拟器LT1的一部分，LT1还包括一个描述CGM传感器、输液泵和患者生理的模型库。因此，控制器可以在各种闭环配置中进行广泛的测试。此外，图形用户界面使其能够集成到教育工具中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IFAC-PapersOnLine Engineering-Control and Systems Engineering

CiteScore

1.70

自引率

0.00%

发文量

1122

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