Antiseptics Prescription for the Prevention and Treatment of Periodontal Diseases: A Comprehensive Review

IF 2.1 Q2 MEDICINE, GENERAL & INTERNAL

Health Science Reports Pub Date : 2025-07-09 DOI:10.1002/hsr2.71019

Lamiae Costo, Mariam Mounsif, Lamiaa Abdallaoui Maan, Amal Bouziane

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Abstract

Background and Aims

Antiseptics have been widely used in periodontology and implantology as an adjunct to mechanical plaque control. The main objective of this review was to summarize the best evidence for the use of antiseptics in the prevention and treatment of periodontal and peri-implant diseases.

Methods

A comprehensive literature search was conducted across multiple databases, including Scopus, PubMed/Medline, Web of Science, and ScienceDirect. Keywords such as (Antiseptics OR mouthwashes) AND (gingivitis OR periodontitis OR peri-implantitis OR mucositis) were used. Inclusion criteria included narrative or systematic reviews with or without meta-analysis and clinical studies. In vitro, animal studies, and case reports were excluded.

Results

Antiseptics, including chlorhexidine, essential oils, and povidone-iodine, proved effective in reducing gingival inflammation and improving the plaque index. Other molecules, such as octenidine dihydrochloride, showed some effectiveness, although further studies are needed to expand their use.

Conclusion

Antiseptics play a crucial role in improving periodontal health. Prescriptions should be tailored to therapeutic goals to ensure appropriate dosage and duration, while avoiding excessive use.

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预防和治疗牙周病的抗菌处方综述

背景与目的杀菌剂作为机械菌斑控制的辅助手段，已广泛应用于牙周病学和种植学。本综述的主要目的是总结使用防腐剂预防和治疗牙周和种植体周围疾病的最佳证据。方法采用Scopus、PubMed/Medline、Web of Science、ScienceDirect等数据库进行文献检索。关键词为（防腐剂或漱口水）、（牙龈炎或牙周炎或种植周炎或粘膜炎）。纳入标准包括有或没有荟萃分析和临床研究的叙述性或系统性综述。体外、动物研究和病例报告均被排除在外。结果氯己定、挥发油、聚维酮碘等防腐剂均能有效减轻牙龈炎症，改善菌斑指数。其他分子，如盐酸辛替尼定，显示出一些效果，尽管需要进一步的研究来扩大它们的使用。结论抗菌药物对牙周健康具有重要的促进作用。处方应根据治疗目标量身定制，以确保适当的剂量和持续时间，同时避免过度使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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