Surgical management of giant neurofibroma in a pediatric patient: A case report.

Abstract

Neurofibromas are benign peripheral nerve sheath tumors that occur in individuals with neurofibromatosis type 1. In pediatric patients, giant neurofibromas pose significant management challenges due to their large size and potential to cause functional impairments. Given their characteristic radiation resistance, indolent growth, and limited chemosensitivity, surgical intervention is frequently required to alleviate tumor-related symptoms, restore function, and mitigate complications. The two primary surgical difficulties are the high recurrence rates resulting from the infiltrative nature of giant neurofibromas and the risk of massive intraoperative hemorrhage. This case report details the surgical management of a pediatric giant neurofibroma, highlighting the multidisciplinary strategy and operative techniques employed to achieve optimal results.