Prevalence of children's mental health disorders and implications in pharmacotherapy: a systematic review and meta-analysis.

Xiangyu Zhao, Luofei Zhang, Laurie Kramer, Bode Wang, Ming Guan, Qing Ma
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Abstract

Introduction: Childhood and adolescence are critical stages during which mental health disorders may develop and profoundly impact individuals and families in the future. Understanding the prevalence and distribution of these disorders is crucial for public health policies and interventions. This analysis aims to summarize current evidence of the prevalence and geographic distribution of mental health disorders among children and adolescents to inform the development of effective psychopharmacological treatments.

Methods: The data were systematically gathered from the most commonly used databases worldwide, including PubMed, PsycINFO, EMBASE, PSYNDEX, MEDLINE, and the Global Burden of Disease (GBD), as well as from current literature to ensure comprehensive coverage. The studies using standardized assessment procedures and recognized diagnostic standards (i.e. DSM, DC, SDQ) were included in the final analysis.

Findings: Our findings indicated that the prevalence of mental health disorders in children and adolescents is higher than previously reported and varies widely across the regions. The analysis underlines the imperative for extensive, culturally attuned research and fortifies the call for global cooperation to surmount the challenges posed by these mental health disorders. It accentuates the need to appreciate the intricate interplay of cultural, socioeconomic, and healthcare factors to improve mental healthcare infrastructure and endorse equitable care access worldwide.

Conclusion: The pursuit of evidence-based public health policies and pharmacotherapy is deemed crucial for improving the prevention and management of mental illnesses in children and adolescents.

儿童心理健康障碍的患病率及其对药物治疗的影响:一项系统回顾和荟萃分析。
童年和青春期是精神健康障碍可能发展并在未来深刻影响个人和家庭的关键阶段。了解这些疾病的患病率和分布对公共卫生政策和干预措施至关重要。本分析旨在总结儿童和青少年心理健康障碍患病率和地理分布的现有证据,为开发有效的心理药理学治疗提供信息。方法:系统地从全球最常用的数据库PubMed、PsycINFO、EMBASE、PSYNDEX、MEDLINE和全球疾病负担(GBD)数据库以及当前文献中收集数据,以确保全面覆盖。采用标准化评估程序和公认诊断标准(即DSM、DC、SDQ)的研究纳入最终分析。研究结果:我们的研究结果表明,儿童和青少年中精神健康障碍的患病率高于之前的报道,并且在不同地区差异很大。该分析强调,必须进行广泛的、与文化相适应的研究,并进一步呼吁开展全球合作,以克服这些精神健康障碍带来的挑战。它强调需要了解文化、社会经济和医疗保健因素之间错综复杂的相互作用,以改善精神卫生保健基础设施,并在全球范围内支持公平的护理机会。结论:追求循证公共卫生政策和药物治疗对于改善儿童和青少年精神疾病的预防和管理至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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