New sesquiterpene derivatives from stems and leaves of Smallanthus sonchifolius.

IF 1.9 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2025-07-05 DOI:10.1080/14786419.2025.2528154

Pham Thi Mai Huong, Do Hoang Anh, Le Thi Vien, Tran Thi Hong Hanh, Nguyen The Cuong, Nguyen Xuan Cuong, Nguyen Hoai Nam

引用次数: 0

Abstract

From the MeOH residue of Smallanthus sonchifolius stems and leaves, three new sesquiterpene derivatives, namely smallantholides A - C (1 - 3), and two know phenyl propanoid glycosides (4 and 5), were isolated using various chromatographic techniques. The structural elucidation was confirmed by spectroscopic methods including 1D, 2D NMR, CD and HR-TOF-MS. Moreover, the in vitro α-glucosidase inhibitory activity of 1 - 5 was also evaluated.

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小红花茎叶的倍半萜新衍生物。

从小红花茎叶MeOH残基中分离得到3个新的倍半萜衍生物，分别为小红花内酯A - C（1 - 3）和2个已知的苯丙苷（4和5）。通过1D， 2D NMR， CD和HR-TOF-MS等光谱方法证实了结构的解析。此外，还对1 - 5的体外α-葡萄糖苷酶抑制活性进行了评价。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.