Quality of life, insomnia, attitudes and beliefs in women undergoing chemotherapy for breast cancer: a cross-sectional study in Amol city Northern Iran.
Mohammad Eslamijouybari, Vipin Patidar, Shiv Kumar Mudgal, Rakhi Gaur, Zohreh Hosseini Marznaki, Andrew Fournier, Mohammad Hossein Hakimi, Sahar Khosravi
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引用次数: 0
Abstract
Background: Breast cancer is the most common disease in women worldwide, and it can cause serious physical and psychological problems, particularly in Iran, where it accounts for 23.6% of all malignancies in women. The goal of the current study was to examine the quality of life, insomnia, attitudes and beliefs in women undergoing chemotherapy for breast cancer.
Methods: A correlational study among 468 breast cancer patients (Stages I-III) selected through convenient sampling in northern Iran was conducted in 2024 to measure quality of life (QoL), insomnia, and patients' attitudes and beliefs toward cancer via the EORTC QLQ-C30, the Insomnia Severity Index (ISI), and the Cancer Attitude and Belief Questionnaire, respectively. Validity and reliability of all instruments were confirmed via content validity index and Cronbach's α respectively. Normality of data was assessed via kurtosis, skewness and Q-Q plots. The data analysis was performed via SPSS Version 24.0 through ordinal logistic regression analyses and Gamma-Cramer correlations.
Results: The individuals (mean age: 45.03 ± 10.57 years) had a high quality of life (81.46 ± 21.4) and mild insomnia (10.54 ± 5.86). QoL was significantly negatively correlated with both insomnia (r=-0.147; p value < 0.05) and patients' attitudes/beliefs toward cancer (r=-0.653; p value < 0.05). Low socioeconomic status had a substantial impact on low QoL (OR = 16.94, p < 0.001) and higher levels of insomnia (OR = 0.35, p = 0.024).
Conclusion: This study emphasizes the need for comprehensive, culturally responsive healthcare treatments by highlighting the many aspects that affect the quality of life of patients with breast cancer receiving chemotherapy, as more than half of the patients reported insomnia problems.
背景：乳腺癌是全世界妇女中最常见的疾病，可引起严重的身体和心理问题，特别是在伊朗，它占妇女所有恶性肿瘤的23.6%。目前这项研究的目的是调查接受乳腺癌化疗的女性的生活质量、失眠、态度和信念。方法：采用便捷抽样方法，于2024年在伊朗北部选取468例I-III期乳腺癌患者进行相关研究，分别通过EORTC QLQ-C30、失眠严重程度指数（ISI）和癌症态度与信念问卷，测量患者的生活质量（QoL）、失眠症和对癌症的态度与信念。采用内容效度指数和Cronbach’s α分别对所有工具进行效度和信度验证。通过峰度、偏度和Q-Q图评估数据的正态性。数据分析采用SPSS Version 24.0，采用有序逻辑回归分析和Gamma-Cramer相关分析。结果：患者平均年龄45.03±10.57岁，生活质量高（81.46±21.4）岁，轻度失眠（10.54±5.86）岁。生活质量与失眠均呈显著负相关(r=-0.147；结论：由于超过一半的乳腺癌患者报告有失眠问题，因此本研究强调需要全面的、符合文化的医疗保健治疗，突出了影响接受化疗的乳腺癌患者生活质量的许多方面。
期刊介绍：
BMC Women''s Health is an open access, peer-reviewed journal that considers articles on all aspects of the health and wellbeing of adolescent girls and women, with a particular focus on the physical, mental, and emotional health of women in developed and developing nations. The journal welcomes submissions on women''s public health issues, health behaviours, breast cancer, gynecological diseases, mental health and health promotion.
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