Outpatient Intravenous Dobutamine as Right Ventricular Support During Inhaled Prostacyclin Uptitration in Severe PH-ILD.

IF 2.2 4区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Pulmonary Circulation Pub Date : 2025-07-02 eCollection Date: 2025-07-01 DOI:10.1002/pul2.70111

A Kumar, Siddharth V Ramanan, Brett Carollo, Kristen Swanson, Raj Parikh

引用次数: 0

Abstract

PH-ILD carries a poor prognosis, particularly with PVR > 5 WU. The INCREASE trial demonstrated the successful use of inhaled treprostinil, but slow uptitration delays the effects. Our study suggests outpatient IV dobutamine as interim support, improving contractility and reducing PVR during uptitration.

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门诊静脉注射多巴酚丁胺作为严重PH-ILD患者吸入前列环素时的右心室支持。

PH-ILD预后较差，尤其是PVR患者。INCREASE试验表明吸入曲前列地尼的使用是成功的，但缓慢的上升延迟了效果。我们的研究建议门诊静脉注射多巴酚丁胺作为临时支持，改善收缩力和降低PVR在上升。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pulmonary Circulation Medicine-Pulmonary and Respiratory Medicine

CiteScore

4.20

自引率

11.50%

发文量

153

审稿时长

15 weeks

期刊介绍： Pulmonary Circulation''s main goal is to encourage basic, translational, and clinical research by investigators, physician-scientists, and clinicans, in the hope of increasing survival rates for pulmonary hypertension and other pulmonary vascular diseases worldwide, and developing new therapeutic approaches for the diseases. Freely available online, Pulmonary Circulation allows diverse knowledge of research, techniques, and case studies to reach a wide readership of specialists in order to improve patient care and treatment outcomes.