Diagnosis and Treatment of HFE^C282Y-Linked Hemochromatosis.

4区医学 Q2 Biochemistry, Genetics and Molecular Biology

Advances in experimental medicine and biology Pub Date : 2025-01-01 DOI:10.1007/978-3-031-92033-2_9

Paul C Adams

引用次数: 0

Abstract

Genetic variants for hemochromatosis have been identified in human fossils that are over 4000 years old in Northern Ireland. Iron overload can lead to life-threatening complications, including liver fibrosis, cirrhosis, and hepatocellular carcinoma. In this review, the emphasis is on developments in the diagnosis and treatment of C282Y-linked hemochromatosis. There is a need for earlier diagnosis leading to earlier treatment to prevent morbidity and mortality.

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hfec282y型血色素沉着症的诊断与治疗。

在北爱尔兰发现的4000多年前的人类化石中，发现了血色素沉着症的遗传变异。铁超载可导致危及生命的并发症，包括肝纤维化、肝硬化和肝细胞癌。本文就c282y型血色素沉着症的诊断和治疗进展作一综述。有必要进行早期诊断，从而进行早期治疗，以预防发病率和死亡率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in experimental medicine and biology 医学-医学：研究与实验

CiteScore

5.90

自引率

0.00%

发文量

465

审稿时长

2-4 weeks

期刊介绍： Advances in Experimental Medicine and Biology provides a platform for scientific contributions in the main disciplines of the biomedicine and the life sciences. This series publishes thematic volumes on contemporary research in the areas of microbiology, immunology, neurosciences, biochemistry, biomedical engineering, genetics, physiology, and cancer research. Covering emerging topics and techniques in basic and clinical science, it brings together clinicians and researchers from various fields.

Diagnosis and Treatment of HFEC282Y-Linked Hemochromatosis.

Abstract

Diagnosis and Treatment of HFE^C282Y-Linked Hemochromatosis.