Judicaël Obame-Nkoghe, Faël Moudoumi Kondji, El Hadji Diouf, Omar Thiaw, Brad Ghaven Niangui, Arnauld Ondo-Oyono, Yasmine Okomo-Nguema, Neil Michel Longo-Pendy, Franck Mounioko, Boris Makanga, Basile Kamgang, Christophe Paupy, Pierre Kengne, Patricks Voua Otomo, El Hadji Amadou Niang
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引用次数: 0
Abstract
The spread of resistance to insecticides, such as pyrethroids, in Aedes vectors increases the risk of spread of arboviral diseases. In Gabon, the insecticide resistance profiles of Ae. aegypti and Ae. albopictus species remain poorly known. During a study to monitor the dynamics of Aedes populations in Franceville, in south-east Gabon, the resistance profiles of these two species to pyrethroids, organophosphates and carbamates were assessed. Susceptibility tests on adults and synergist tests with piperonyl butoxide (PBO) were carried out as per the World Health Organization protocol. The results showed that Ae. aegypti and Ae. albopictus were susceptible to permethrin, pirimiphos-methyl and bendiocarb. However, both species were resistant to deltamethrin (mortality: 67% for Ae. aegypti; 33% for Ae. albopictus). Exposure to a 5-fold dose of deltamethrin increased mortality to 100% and 91% for Ae. aegypti and Ae. albopictus, respectively. Resistance to alpha-cypermethrin was also recorded (mortality: 82% for Ae. aegypti; 64.6% for Ae. albopictus). Pre-exposure to PBO resulted in the restoration of susceptibility to deltamethrin and alpha-cypermethrin for Ae. aegypti, and a significant increase in mortality for Ae. albopictus. These data provide the first evidence of pyrethroid resistance in Aedes in Gabon and could help to establish more effective control measures against arbovirus vectors.
期刊介绍：
Parasite is an international open-access, peer-reviewed, online journal publishing high quality papers on all aspects of human and animal parasitology. Reviews, articles and short notes may be submitted. Fields include, but are not limited to: general, medical and veterinary parasitology; morphology, including ultrastructure; parasite systematics, including entomology, acarology, helminthology and protistology, and molecular analyses; molecular biology and biochemistry; immunology of parasitic diseases; host-parasite relationships; ecology and life history of parasites; epidemiology; therapeutics; new diagnostic tools.
All papers in Parasite are published in English. Manuscripts should have a broad interest and must not have been published or submitted elsewhere. No limit is imposed on the length of manuscripts, but they should be concisely written. Papers of limited interest such as case reports, epidemiological studies in punctual areas, isolated new geographical records, and systematic descriptions of single species will generally not be accepted, but might be considered if the authors succeed in demonstrating their interest.
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