Yanan Xu, Ruien Li, Lequn Zhang, Xueyuan Bai and Wei Zhang
{"title":"Advancements in gas chromatography-ion mobility spectrometry for analysing natural medicines","authors":"Yanan Xu, Ruien Li, Lequn Zhang, Xueyuan Bai and Wei Zhang","doi":"10.1039/D5AY00439J","DOIUrl":null,"url":null,"abstract":"<p >Gas chromatography-ion mobility spectrometry (GC-IMS) is an emerging analytical technique with significant potential for natural medicine analysis because of its high sensitivity, resolution, rapid detection, and portability. This article discusses the principles of GC-IMS technology and its diverse applications in analysing natural medicine compositions. These applications encompass authenticity, origin, matrix, quality determination, and identification of volatile compounds. Additionally, the potential of combining GC-IMS with other analytical techniques is investigated. Finally, the current challenges facing the adoption of GC-IMS for natural medicine discovery and characterisation are presented alongside future development directions. This article primarily aims to provide a comprehensive reference for applying GC-IMS technology in the analysis of natural medicine components and foster continued advancements in natural medicine research.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 27","pages":" 5621-5635"},"PeriodicalIF":2.6000,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Methods","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2025/ay/d5ay00439j","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Gas chromatography-ion mobility spectrometry (GC-IMS) is an emerging analytical technique with significant potential for natural medicine analysis because of its high sensitivity, resolution, rapid detection, and portability. This article discusses the principles of GC-IMS technology and its diverse applications in analysing natural medicine compositions. These applications encompass authenticity, origin, matrix, quality determination, and identification of volatile compounds. Additionally, the potential of combining GC-IMS with other analytical techniques is investigated. Finally, the current challenges facing the adoption of GC-IMS for natural medicine discovery and characterisation are presented alongside future development directions. This article primarily aims to provide a comprehensive reference for applying GC-IMS technology in the analysis of natural medicine components and foster continued advancements in natural medicine research.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
