West Nile morbidity and mortality in a Mid-Atlantic healthcare system, 2013-2024.

Abstract

We investigated West Nile cases in a Mid-Atlantic healthcare system, finding significant morbidity and mortality from neuroinvasive disease, notably among immunocompromised patients. Encephalitis was the most common complication and was associated with increased age, alcohol use disorder, immunocompromised status, and a higher Charlson Comorbidity Index.