Nanomaterial-based gene delivery in plants: an upcoming genetic revolution?

IF 17.3 1区 生物学 Q1 PLANT SCIENCES
Nidhi Kandhol, Prasanta K Dash, Vijay Pratap Singh, Rupesh Deshmukh, Om Parkash Dhankher, Lam-Son Phan Tran, Jason C White, Durgesh Kumar Tripathi
{"title":"Nanomaterial-based gene delivery in plants: an upcoming genetic revolution?","authors":"Nidhi Kandhol, Prasanta K Dash, Vijay Pratap Singh, Rupesh Deshmukh, Om Parkash Dhankher, Lam-Son Phan Tran, Jason C White, Durgesh Kumar Tripathi","doi":"10.1016/j.tplants.2025.04.012","DOIUrl":null,"url":null,"abstract":"<p><p>Conventional gene-delivery methods in plant genetic engineering, such as electroporation and Agrobacterium-mediated transformation, face limitations such as species dependency, low efficiency, high cost, and undesirable DNA integration into the host genome. Integrating nanotechnology with existing molecular techniques offers a promising solution. Nanocarriers can precisely target tissues, cells, and organelles by penetrating biological barriers and protecting the cargo from degradation. The nanocarrier-based gene delivery approach addresses challenges, such as collateral damage and inefficient DNA integration, and paves the way for the development of crops with desired traits. Future research should optimize nanocarriers for efficient and precise gene delivery while minimizing off-target effects. Sustainable, cost-effective materials can enhance large-scale agricultural applications, thereby revolutionizing crop production for global food security and advancing sustainable practices.</p>","PeriodicalId":23264,"journal":{"name":"Trends in Plant Science","volume":" ","pages":""},"PeriodicalIF":17.3000,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Plant Science","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.tplants.2025.04.012","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Conventional gene-delivery methods in plant genetic engineering, such as electroporation and Agrobacterium-mediated transformation, face limitations such as species dependency, low efficiency, high cost, and undesirable DNA integration into the host genome. Integrating nanotechnology with existing molecular techniques offers a promising solution. Nanocarriers can precisely target tissues, cells, and organelles by penetrating biological barriers and protecting the cargo from degradation. The nanocarrier-based gene delivery approach addresses challenges, such as collateral damage and inefficient DNA integration, and paves the way for the development of crops with desired traits. Future research should optimize nanocarriers for efficient and precise gene delivery while minimizing off-target effects. Sustainable, cost-effective materials can enhance large-scale agricultural applications, thereby revolutionizing crop production for global food security and advancing sustainable practices.

基于纳米材料的植物基因传递:一场即将到来的基因革命?
在植物基因工程中,传统的基因传递方法,如电穿孔和农杆菌介导的转化,面临着物种依赖性、低效率、高成本和不希望DNA整合到宿主基因组中的局限性。将纳米技术与现有的分子技术相结合提供了一个有希望的解决方案。纳米载体可以通过穿透生物屏障和保护货物免受降解,精确地靶向组织、细胞和细胞器。基于纳米载体的基因传递方法解决了诸如附带损害和低效DNA整合等挑战,并为开发具有所需性状的作物铺平了道路。未来的研究应优化纳米载体,以实现高效、精确的基因传递,同时最大限度地减少脱靶效应。可持续的、具有成本效益的材料可以加强大规模农业应用,从而彻底改变作物生产,促进全球粮食安全,并促进可持续做法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Trends in Plant Science
Trends in Plant Science 生物-植物科学
CiteScore
31.30
自引率
2.00%
发文量
196
审稿时长
6-12 weeks
期刊介绍: Trends in Plant Science is the primary monthly review journal in plant science, encompassing a wide range from molecular biology to ecology. It offers concise and accessible reviews and opinions on fundamental plant science topics, providing quick insights into current thinking and developments in plant biology. Geared towards researchers, students, and teachers, the articles are authoritative, authored by both established leaders in the field and emerging talents.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信