{"title":"Upadacitinib for the Treatment of Upper Gastrointestinal Crohn's Disease.","authors":"Bader AlBader, Rishi Jairath, Haneen Baitalmal, Talat Bessissow","doi":"10.14309/crj.0000000000001749","DOIUrl":null,"url":null,"abstract":"<p><p>Data on the use of antitumor necrosis factor therapy have shown some positive outcomes in case reports or small observational studies such as the data showing the benefit of adalimumab in this rare presentation of Crohn's disease. To our knowledge, there is no published data on the use of upadacitinib in the treatment of upper gastrointestinal Crohn's disease. We present a case report of a young patient with severe oral and esophageal Crohn's disease that was successfully treated with upadacitinib.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01749"},"PeriodicalIF":0.5000,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204142/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACG Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14309/crj.0000000000001749","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Data on the use of antitumor necrosis factor therapy have shown some positive outcomes in case reports or small observational studies such as the data showing the benefit of adalimumab in this rare presentation of Crohn's disease. To our knowledge, there is no published data on the use of upadacitinib in the treatment of upper gastrointestinal Crohn's disease. We present a case report of a young patient with severe oral and esophageal Crohn's disease that was successfully treated with upadacitinib.
期刊介绍:
ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.