Emerging connections between myelin and Alzheimer’s disease

IF 19.1 1区生物学 Q1 CELL BIOLOGY

Nature Cell Biology Pub Date : 2025-07-01 DOI:10.1038/s41556-025-01701-1

Anna Bright, Leyla Anne Akay, Joel Blanchard, Li-Huei Tsai

引用次数: 0

Abstract

Recent literature has explored the contributions of oligodendrocytes and myelin dysfunction to Alzheimer’s disease. Here, we discuss emerging evidence that oligodendrocytes may directly contribute to disease pathology and progression.

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髓磷脂与阿尔茨海默病之间的新联系

最近的文献探讨了少突胶质细胞和髓鞘功能障碍对阿尔茨海默病的贡献。在这里，我们讨论新出现的证据，少突胶质细胞可能直接促进疾病的病理和进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Cell Biology 生物-细胞生物学

CiteScore

28.40

自引率

0.90%

发文量

219

审稿时长

3 months

期刊介绍： Nature Cell Biology, a prestigious journal, upholds a commitment to publishing papers of the highest quality across all areas of cell biology, with a particular focus on elucidating mechanisms underlying fundamental cell biological processes. The journal's broad scope encompasses various areas of interest, including but not limited to: -Autophagy -Cancer biology -Cell adhesion and migration -Cell cycle and growth -Cell death -Chromatin and epigenetics -Cytoskeletal dynamics -Developmental biology -DNA replication and repair -Mechanisms of human disease -Mechanobiology -Membrane traffic and dynamics -Metabolism -Nuclear organization and dynamics -Organelle biology -Proteolysis and quality control -RNA biology -Signal transduction -Stem cell biology