C–H functionalisation of [2.2]paracyclophane under copper catalysis†

Abstract

The direct C–H functionalisation of [2.2]paracyclophane (PCP) by forging diverse C–C bonds is appealing, yet has remained underexplored. Herein, we describe a copper-catalysed non-directed C–H arylation and alkenylation of PCP with various iodonium salts. This method features high selectivity, broad substrate scope, and mild conditions, constituting a practical platform for modular access to PCP derivatives.