Luigi Coricciati, Irene Fusco, Alessandra Comito, Jorilda Biba, Tiziano Zingoni
{"title":"Effectiveness of 675 nm Laser in Melasma Treatment: 1-Year Follow-Up.","authors":"Luigi Coricciati, Irene Fusco, Alessandra Comito, Jorilda Biba, Tiziano Zingoni","doi":"10.1089/photob.2025.0044","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Background:</i></b> Melasma is a cutaneous pigmentary condition, difficult to treat due to its multifactorial chronic nature and high recurrence rates. <b><i>Objective:</i></b> To investigate the medium-term and long-term efficacy of the 675 nm laser for the treatment of facial melasma with pigmentary and vascular symptoms. <b><i>Methods:</i></b> Eight patients with facial melasma and Fitzpatrick phototypes III to IV were recruited. Three sessions were carried out with a 675-nm laser device. At 5 months and 12 months after the last treatment, the patient's skin was evaluated from baseline using a five-point Global Aesthetic Improvement Scale (GAIS). <b><i>Results:</i></b> The study findings revealed a better overall appearance of the skin condition, in particular GAIS improvements mainly in the visible and pigmented components. <b><i>Conclusion:</i></b> The 675-nm laser appears to be effective when treating patients with Fitzpatrick phototypes III to IV for facial melasma, with promising long-term results.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photobiomodulation, photomedicine, and laser surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1089/photob.2025.0044","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Melasma is a cutaneous pigmentary condition, difficult to treat due to its multifactorial chronic nature and high recurrence rates. Objective: To investigate the medium-term and long-term efficacy of the 675 nm laser for the treatment of facial melasma with pigmentary and vascular symptoms. Methods: Eight patients with facial melasma and Fitzpatrick phototypes III to IV were recruited. Three sessions were carried out with a 675-nm laser device. At 5 months and 12 months after the last treatment, the patient's skin was evaluated from baseline using a five-point Global Aesthetic Improvement Scale (GAIS). Results: The study findings revealed a better overall appearance of the skin condition, in particular GAIS improvements mainly in the visible and pigmented components. Conclusion: The 675-nm laser appears to be effective when treating patients with Fitzpatrick phototypes III to IV for facial melasma, with promising long-term results.
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