[Peptide bioregulation in prosthetic stomatitis among the elder people.]

Abstract

The study examined the effectiveness of using the peptide complex «Visulingval» in the complex therapy of prosthetic stomatitis in elderly people suffering from complete loss of teeth and using removable acrylic dentures. 52 elderly patients (62-74 years old) who suffered complete loss of teeth in both jaws were examined. The surveyed were divided into 3 groups. The parameters of secretory immunoglobulin A, antimicrobial peptides, as well as the detection of Candida spp. in the oral cavity were studied. Using of the peptide bioregulator in the course of complex therapy of prosthetic stomatitis contributed to an increase in mucosal immunity of the oral mucosa. It should be recognized that it is advisable to use the peptide bioregulator «Visulingval» in elderly patients using full removable acrylic dentures for the prevention and treatment of prosthetic stomatitis.