{"title":"Refractory Infantyl Chylous Ascites Treatment by Everolimus.","authors":"Masallah Baran, Sinem Kahveci, Betul Aksoy, Yeliz Cagan Appak, Gizem Dogan, Hacer Orsdemir Hortu, Gokhan Koyluoglu","doi":"10.4274/MMJ.galenos.2025.82284","DOIUrl":null,"url":null,"abstract":"<p><p>The accumulation of lymphatic fluid in the abdomen is defined as chylous ascites. Different causes play a role in the etiology of the disease. Congenital anomalies are the most common cause in pediatric patients. A high protein, low fat diet rich in medium-chain fatty acids should be planned. The first-line treatment is dietary management and is total parenteral nutrition, and the first preferred medical agent is somatostatin. In patients who do not respond to standard treatments, surgical treatment or new limited alternative medical agents are applied. A six-month-old girl presented with a complaint of abdominal swelling was diagnosed with chylous acid. The patient was put on the standard nutritional therapy and somatostatin treatment but did not respond to these treatments. The chylous ascites was controlled with everolimus treatment.</p>","PeriodicalId":37427,"journal":{"name":"Medeniyet medical journal","volume":"40 2","pages":"110-113"},"PeriodicalIF":1.1000,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12203448/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medeniyet medical journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4274/MMJ.galenos.2025.82284","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
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Abstract
The accumulation of lymphatic fluid in the abdomen is defined as chylous ascites. Different causes play a role in the etiology of the disease. Congenital anomalies are the most common cause in pediatric patients. A high protein, low fat diet rich in medium-chain fatty acids should be planned. The first-line treatment is dietary management and is total parenteral nutrition, and the first preferred medical agent is somatostatin. In patients who do not respond to standard treatments, surgical treatment or new limited alternative medical agents are applied. A six-month-old girl presented with a complaint of abdominal swelling was diagnosed with chylous acid. The patient was put on the standard nutritional therapy and somatostatin treatment but did not respond to these treatments. The chylous ascites was controlled with everolimus treatment.
期刊介绍：
The Medeniyet Medical Journal (Medeniyet Med J) is an open access, peer-reviewed, and scientific journal of Istanbul Medeniyet University Faculty of Medicine on various academic disciplines in medicine, which is published in English four times a year, in March, June, September, and December by a group of academics. Medeniyet Medical Journal is the continuation of Göztepe Medical Journal (ISSN: 1300-526X) which was started publishing in 1985. It changed the name as Medeniyet Medical Journal in 2015. Submission and publication are free of charge. No fees are asked from the authors for evaluation or publication process. All published articles are available online in the journal website (www.medeniyetmedicaljournal.org) without any fee. The journal publishes intradisciplinary or interdisciplinary clinical, experimental, and basic researches as well as original case reports, reviews, invited reviews, or letters to the editor, Being published since 1985, the Medeniyet Med J recognizes that the best science should lead to better lives based on the fact that the medicine should serve to the needs of society, and knowledge should transform society. The journal aims to address current issues at both national and international levels, start debates, and exert an influence on decision-makers all over the world by integrating science in everyday life. Medeniyet Med J is committed to serve the public and influence people’s lives in a positive way by making science widely accessible. Believing that the only goal is improving lives, and research has an impact on people’s lives, we select the best research papers in line with this goal.
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