Molecular detection and isolation of clade Ib monkeypox virus, Canada, November 2024.

IF 9.9 2区医学 Q1 INFECTIOUS DISEASES

Eurosurveillance Pub Date : 2025-06-01 DOI:10.2807/1560-7917.ES.2025.30.25.2500402

Mable Chan, Jonathan Audet, Jérémie Prévost, Karla Soriano, Kaylie Doan, Lauren Garnett, Yvon Deschambault, Sarah Medina, Marianne Stefopulos, Julia Paul, Santina Lee, Carol Kurbis, Bunmi Fatoye, Ana T Duggan, Katherine Eaton, Connor Chato, Darian Hole, Amber Papineau, Kerry Dust, Paul Van Caeseele, Yonette R Hercules, Shannon Gearhart, John Embil, Andrew Walkty, Donna Romaniuk, David Safronetz, James E Strong

引用次数: 0

Abstract

In November 2024, a case of clade Ib mpox was confirmed in Canada. Here, we describe the events that led to laboratory confirmation of clade Ib monkeypox virus (MPXV) and the public health response. Genomic analysis of the Canadian clade Ib MPXV revealed a number of APOBEC3-related mutations suggesting sustained human-to-human transmission. These findings expand the number of countries with travel-related clade Ib mpox and highlights the continued need for mpox monitoring of potential human adaptations or new transmission patterns.

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猴痘b枝病毒的分子检测与分离，加拿大，2024年11月。

2024年11月，加拿大确认了一例乙型天花病例。在此，我们描述导致实验室确认b支猴痘病毒（MPXV）的事件和公共卫生应对措施。加拿大分支Ib MPXV的基因组分析显示，许多apobec3相关突变表明持续的人传人。这些发现扩大了存在与旅行有关的b支m痘的国家数量，并强调继续需要对潜在的人类适应或新的传播模式进行m痘监测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eurosurveillance INFECTIOUS DISEASES-

CiteScore

32.70

自引率

2.10%

发文量

430

审稿时长

3-8 weeks

期刊介绍： Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.