Imaging of Immunodeficiency-Associated Lymphoproliferative Disorders

IF 1.9 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Seminars in Ultrasound Ct and Mri Pub Date : 2025-06-19 DOI:10.1053/j.sult.2025.06.001

Tomás Franquet MD, PhD , Jose M. Brenes MD , Monika Radike MD, PhD , Ana Giménez MD , Pere Domingo MD, PhD

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引用次数: 0

Abstract

Immunodeficiency-associated lymphoproliferative disorders represent a heterogeneous group of conditions characterized by abnormal lymphoid tissue proliferation in the context of immune dysregulation. These disorders can range from benign reactive hyperplasia to overt malignant lymphoma and are strongly associated with conditions such as congenital and acquired immunodeficiencies, chronic immunosuppressive therapy, and viral infections, particularly Epstein-Barr virus. This article provides a comprehensive overview of the most common immunodeficiency-associated lymphoproliferative disorders subtypes, their pathogenesis, imaging features, and clinical management. The role of high-resolution computed tomography in the detection, characterization, and differential diagnosis of these entities is highlighted, with a focus on practical radiologic-pathologic correlations.

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免疫缺陷相关淋巴细胞增生性疾病的影像学研究。

免疫缺陷相关淋巴细胞增生性疾病（ia - lpd）代表了一组异质性的疾病，其特征是免疫失调背景下淋巴组织增生异常。这些疾病的范围从良性反应性增生到显性恶性淋巴瘤，并与先天性和获得性免疫缺陷、慢性免疫抑制治疗和病毒感染，特别是eb病毒（EBV）等疾病密切相关。本文提供了最常见的IA-LPD亚型、发病机制、影像学特征和临床管理的全面概述。高分辨率计算机断层扫描（HRCT）在这些实体的检测、表征和鉴别诊断中的作用被强调，重点是实际的放射学-病理学相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in Ultrasound Ct and Mri 医学-核医学

CiteScore

2.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Seminars in Ultrasound, CT and MRI is directed to all physicians involved in the performance and interpretation of ultrasound, computed tomography, and magnetic resonance imaging procedures. It is a timely source for the publication of new concepts and research findings directly applicable to day-to-day clinical practice. The articles describe the performance of various procedures together with the authors'' approach to problems of interpretation.