Challenges of alignment in synthetic cell research.

IF 14.9 1区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Trends in biotechnology Pub Date : 2025-09-01 Epub Date: 2025-06-20 DOI:10.1016/j.tibtech.2025.05.024

M G J L Habets, H A E Zwart, M H Smolka

引用次数: 0

Abstract

Big Science projects are often troubled by misalignments. We analyze how synthetic cell researchers handle misalignments by performing alignment work. We find that alignment work renders Big Science feasible, but involves trade-offs, for example between short-term successes and long-term goals. We thus recommend attending to the politics of alignment work.

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合成细胞研究中对齐的挑战。

大的科学项目经常被错位所困扰。我们分析了合成细胞研究人员如何通过执行校准工作来处理错位。我们发现校准工作使大科学变得可行，但是涉及到权衡，例如短期成功和长期目标之间的权衡。因此，我们建议注意协调工作的政治问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in biotechnology 工程技术-生物工程与应用微生物

CiteScore

28.60

自引率

1.20%

发文量

198

审稿时长

1 months

期刊介绍： Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems. The major themes that TIBTECH is interested in include: Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering) Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology) Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics) Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery) Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).