Advancements in Engineering Tetrahedral Framework Nucleic Acids for Biomedical Innovations (Small Methods 6/2025)

IF 10.7 2区材料科学 Q1 CHEMISTRY, PHYSICAL

Small Methods Pub Date : 2025-06-22 DOI:10.1002/smtd.202570039

Qin Fan, Bicheng Sun, Jie Chao

引用次数: 0

Abstract

Inside Back Cover

In article number 2401360, Chao and co-workers review the engineering of tetrahedral framework nucleic acids (tFNAs) for biomedical applications, emphasizing their structural stability, programmability, and cellular permeability. Their roles in immunoregulation, ROS scavenging, anti-apoptotic functions, and as nanocarriers for diverse therapeutic agents are discussed. Additionally, it highlights the potential of bioresponsive tFNAs for spatiotemporal drug release.

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生物医学创新工程四面体框架核酸研究进展（小方法6/2025）

在文章编号2401360中，Chao及其同事回顾了四面体框架核酸（tFNAs）在生物医学上的应用，强调了它们的结构稳定性、可编程性和细胞渗透性。讨论了它们在免疫调节、活性氧清除、抗凋亡功能以及作为多种治疗剂的纳米载体中的作用。此外，它还强调了生物反应性tfna在时空药物释放方面的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Small Methods Materials Science-General Materials Science

CiteScore

17.40

自引率

1.60%

发文量

347

期刊介绍： Small Methods is a multidisciplinary journal that publishes groundbreaking research on methods relevant to nano- and microscale research. It welcomes contributions from the fields of materials science, biomedical science, chemistry, and physics, showcasing the latest advancements in experimental techniques. With a notable 2022 Impact Factor of 12.4 (Journal Citation Reports, Clarivate Analytics, 2023), Small Methods is recognized for its significant impact on the scientific community. The online ISSN for Small Methods is 2366-9608.