The long run: A tribute to Arthur Joseph Lawrence Cooper

IF 2.6 4区生物学 Q2 BIOCHEMICAL RESEARCH METHODS

Analytical biochemistry Pub Date : 2025-06-19 DOI:10.1016/j.ab.2025.115926

John T. Pinto , Thambi Dorai , Thomas M. Jeitner , Travis T. Denton

引用次数: 0

Abstract

In this issue of Analytical Biochemistry, we honor the life and legacy of Arthur Joseph Lawrence Cooper (1946–2024). Born in London, Arthur made pioneering contributions to medical science, particularly in understanding the role of glutamine in the brain and cancer cell metabolism. His research revealed how glutamine supports neurotransmitter synthesis, energy production, and ammonia detoxification, as well as its critical role in cancer cell growth. His work has greatly advanced both neuroscience and cancer biology, offering insights that could lead to new therapeutic strategies targeting glutamine metabolism.

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《漫漫长路：致敬亚瑟·约瑟夫·劳伦斯·库珀》

在本期的《分析生物化学》中，我们向亚瑟·约瑟夫·劳伦斯·库珀（1946-2024）的一生和遗产致敬。亚瑟出生于伦敦，对医学科学做出了开创性的贡献，特别是在理解谷氨酰胺在大脑和癌细胞代谢中的作用方面。他的研究揭示了谷氨酰胺如何支持神经递质合成、能量产生和氨解毒，以及它在癌细胞生长中的关键作用。他的工作极大地推动了神经科学和癌症生物学的发展，提供了可能导致针对谷氨酰胺代谢的新治疗策略的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Analytical biochemistry 生物-分析化学

CiteScore

5.70

自引率

0.00%

发文量

283

审稿时长

44 days

期刊介绍： The journal''s title Analytical Biochemistry: Methods in the Biological Sciences declares its broad scope: methods for the basic biological sciences that include biochemistry, molecular genetics, cell biology, proteomics, immunology, bioinformatics and wherever the frontiers of research take the field. The emphasis is on methods from the strictly analytical to the more preparative that would include novel approaches to protein purification as well as improvements in cell and organ culture. The actual techniques are equally inclusive ranging from aptamers to zymology. The journal has been particularly active in: -Analytical techniques for biological molecules- Aptamer selection and utilization- Biosensors- Chromatography- Cloning, sequencing and mutagenesis- Electrochemical methods- Electrophoresis- Enzyme characterization methods- Immunological approaches- Mass spectrometry of proteins and nucleic acids- Metabolomics- Nano level techniques- Optical spectroscopy in all its forms. The journal is reluctant to include most drug and strictly clinical studies as there are more suitable publication platforms for these types of papers.