Angeliki Margoni, Kostas A. Papavassiliou, Athanasios G. Papavassiliou
{"title":"Implementation of a Multi-Gene Molecular Panel at Fine Needle Aspiration Biopsy (FNAB) Thyroid Samples: A Compelling Diagnostic and Prognostic Model","authors":"Angeliki Margoni, Kostas A. Papavassiliou, Athanasios G. Papavassiliou","doi":"10.1111/cyt.70004","DOIUrl":null,"url":null,"abstract":"<p>Application of a multi-gene panel in FNAB thyroid samples provides a patient-directed diagnostic and prognostic model. Several genetic mutations and molecular markers are correlated with histological subtypes of thyroid cancer, revealing the potential role of molecular techniques in targeted therapy. The combination of FNAB and multi-gene tests introduces clinicians to the benefits of precision oncology.</p>","PeriodicalId":55187,"journal":{"name":"Cytopathology","volume":"36 5","pages":"547-548"},"PeriodicalIF":1.1000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cytopathology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/cyt.70004","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Application of a multi-gene panel in FNAB thyroid samples provides a patient-directed diagnostic and prognostic model. Several genetic mutations and molecular markers are correlated with histological subtypes of thyroid cancer, revealing the potential role of molecular techniques in targeted therapy. The combination of FNAB and multi-gene tests introduces clinicians to the benefits of precision oncology.
期刊介绍:
The aim of Cytopathology is to publish articles relating to those aspects of cytology which will increase our knowledge and understanding of the aetiology, diagnosis and management of human disease. It contains original articles and critical reviews on all aspects of clinical cytology in its broadest sense, including: gynaecological and non-gynaecological cytology; fine needle aspiration and screening strategy.
Cytopathology welcomes papers and articles on: ultrastructural, histochemical and immunocytochemical studies of the cell; quantitative cytology and DNA hybridization as applied to cytological material.