Relationship of the intensity of physical performance and sedentary time with uric acid in patients with type 2 diabetes.

IF 3.2 3区医学

Journal of Diabetes Investigation Pub Date : 2025-06-18 DOI:10.1111/jdi.70106

Jie Li, Ertao Zhang, Zhao Dong, Yan Liu

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引用次数: 0

Abstract

Objective: High uric acid (UA) facilitates diabetes progression and is responsible for developing other diseases, such as cardiovascular disease and renal disease. Lifestyle modifications could lower UA level, but relevant evidence is required in patients with type 2 diabetes. This study intended to explore the influence of different physical activities and sitting time on UA level in patients with type 2 diabetes.

Methods: Data on UA level, physical performance, and sitting time from 1892 patients with type 2 diabetes were retrospectively obtained from the Third People's Hospital of Datong, a subcenter of the Metabolic Management Center (MMC) Central database.

Results: There were 15.8%, 29.7%, 29.5%, and 25.0% of patients with inactive, mild, moderate, and vigorous intensity of physical activity. UA level presented a U-shaped distribution among patients with different intensities of physical activity, with the lowest in patients with mild intensity of physical activity and the highest in patients with vigorous intensity of physical activity (P = 0.007). There were 58.1% and 41.9% of patients with a sitting time of ≤30 h/week and >30 h/week. UA level was lower in patients with sitting time ≤30 h/week than those with sitting time > 30 h/week (P = 0.014). The above findings were confirmed by multivariate linear regression models.

Conclusions: Mild intensity of physical activity and sitting time ≤ 30 h/week are recommended for reducing UA level in patients with type 2 diabetes.

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2型糖尿病患者运动强度和久坐时间与尿酸的关系

目的：高尿酸（UA）促进糖尿病的进展，并负责发展其他疾病，如心血管疾病和肾脏疾病。生活方式改变可降低UA水平，但2型糖尿病患者需要相关证据。本研究旨在探讨不同体育活动和静坐时间对2型糖尿病患者UA水平的影响。方法：从代谢管理中心（MMC）中央数据库分中心——大同市第三人民医院收集1892例2型糖尿病患者的UA水平、身体机能和静坐时间数据。结果：不活跃、轻度、中度、剧烈运动的患者占15.8%、29.7%、29.5%、25.0%。不同运动强度患者UA水平呈u型分布，轻度运动强度患者UA水平最低，剧烈运动强度患者UA水平最高（P = 0.007）。坐下时间≤30 h/周的占58.1%，坐下时间≤30 h/周的占41.9%。静坐时间≤30 h/周的患者UA水平低于静坐时间≤30 h/周的患者（P = 0.014）。以上发现通过多元线性回归模型得到证实。结论：2型糖尿病患者推荐轻度运动强度和坐下时间≤30小时/周降低UA水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Diabetes Investigation Medicine-Internal Medicine

自引率

9.40%

发文量

218

期刊介绍： Journal of Diabetes Investigation is your core diabetes journal from Asia; the official journal of the Asian Association for the Study of Diabetes (AASD). The journal publishes original research, country reports, commentaries, reviews, mini-reviews, case reports, letters, as well as editorials and news. Embracing clinical and experimental research in diabetes and related areas, the Journal of Diabetes Investigation includes aspects of prevention, treatment, as well as molecular aspects and pathophysiology. Translational research focused on the exchange of ideas between clinicians and researchers is also welcome. Journal of Diabetes Investigation is indexed by Science Citation Index Expanded (SCIE).