Promise and pitfalls of liver xenotransplantation

IF 45.9 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Nature Reviews Gastroenterology &Hepatology Pub Date : 2025-06-19 DOI:10.1038/s41575-025-01093-5

Burcin Ekser, Luis A. Fernandez

引用次数: 0

Abstract

Liver xenotransplantation and genetically engineered pig livers have potential to save human lives. Liver xenotransplants can either act as a bridge to allotransplantation or support the recovery and regeneration of a whole or reduced native liver in acute liver failure and in major hepatectomies through ex vivo perfusion or auxiliary liver xenotransplantation.

Abstract Image

查看原文本刊更多论文

异种肝脏移植的前景和缺陷

肝脏异种移植和基因工程猪肝具有挽救人类生命的潜力。异种肝脏移植既可以作为同种异体移植的桥梁，也可以通过体外灌注或辅助肝脏异种移植在急性肝功能衰竭和主要肝切除术中支持整个或减少的天然肝脏的恢复和再生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nature Reviews Gastroenterology &Hepatology 医学-胃肠肝病学

CiteScore

52.30

自引率

0.60%

发文量

147

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Gastroenterology & Hepatology aims to serve as the leading resource for Reviews and commentaries within the scientific and medical communities it caters to. The journal strives to maintain authority, accessibility, and clarity in its published articles, which are complemented by easily understandable figures, tables, and other display items. Dedicated to providing exceptional service to authors, referees, and readers, the editorial team works diligently to maximize the usefulness and impact of each publication. The journal encompasses a wide range of content types, including Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements, all pertinent to gastroenterologists and hepatologists. With its broad scope, Nature Reviews Gastroenterology & Hepatology ensures that its articles reach a diverse audience, aiming for the widest possible dissemination of valuable information. Nature Reviews Gastroenterology & Hepatology is part of the Nature Reviews portfolio of journals.