Annual report of the Australian Gonococcal Surveillance Programme, 2001.

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引用次数: 0

Abstract

The Australian Gonococcal Surveillance Programme monitors the antibiotic susceptibility of Neisseria gonorrhoeae isolated in all States and Territories. In 2001 the in vitro susceptibility of 3,641 isolates of gonococci from public and private sector sources was determined by standardised methods. Antibiotic susceptibility patterns again varied considerably between regions. Resistance to the penicillins remained high in larger urban centres and warrants close attention in those rural centres where treatment with the penicillins continues. Quinolone resistance in gonococci (QRNG) became more widespread in Australia in 2001 and MICs increased. Nationally, 17.5 per cent of all isolates were QRNG. Endemic cycles of transmission of QRNG in homosexually active men declined further, but heterosexual transmission increased substantially. All isolates remained sensitive to spectinomycin. A small number of isolates in a number of jurisdictions again showed some decreased susceptibility to ceftriaxone. A high proportion of gonococci examined in larger urban centres were from male patients, and rectal and pharyngeal isolates were common. In other centres and in rural Australia the male to female ratio of cases was lower, and most isolates were from the genital tract.

2001年澳大利亚淋球菌监测方案年度报告。
澳大利亚淋球菌监测方案监测在所有州和地区分离的淋病奈瑟菌对抗生素的敏感性。2001年,通过标准化方法确定了来自公共和私营部门来源的3,641株淋球菌的体外敏感性。不同地区的抗生素敏感性模式也有很大差异。在较大的城市中心,对青霉素的耐药性仍然很高,在那些继续用青霉素治疗的农村中心,需要密切关注。淋球菌喹诺酮类药物耐药性(QRNG)在2001年澳大利亚变得更加普遍,中等收入国家增加。在全国范围内,17.5%的分离株是QRNG。QRNG在同性恋活跃男性中的传播周期进一步下降,但异性传播显著增加。所有分离株均对大观霉素敏感。在一些司法管辖区的少数分离株再次显示对头孢曲松的敏感性有所下降。在较大的城市中心检查的淋球菌中,来自男性患者的比例很高,直肠和咽分离株很常见。在其他中心和澳大利亚农村,病例的男女比例较低,大多数分离株来自生殖道。
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