APPLICATION VALUE OF DISSECTION PARATHYROIDECTOMY IN PATIENTS WITH CHRONIC KIDNEY DISEASE COMPLICATED BY REFRACTORY SECONDARY HYPERPARATHYROIDISM.

IF 0.7 4区医学 Q4 ENDOCRINOLOGY & METABOLISM

Acta Endocrinologica-Bucharest Pub Date : 2024-07-01 Epub Date: 2025-05-23 DOI:10.4183/aeb.2024.304

L Zhang, Y Chen, Y Ao, Y Qi

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引用次数: 0

Abstract

Objective: To analyze the clinical value of dissection parathyroidectomy (DP) in patients with chronic kidney disease (CKD) complicated by refractory secondary hyperparathyroidism (HPT).

Subjects and methods: Patients with CKD complicated by refractory secondary HPT were included as the research subjects. Among them, 42 patients who received DP were assigned as the study group, while another 42 patients who underwent conventional total parathyroidectomy were assigned as the control group.

Results: The average operative time and postoperative average length of hospital stay of the study group were lower than those of the control group (P<0.05). The study group showed lower levels of parathyroid hormone (PTH) compared to the control group 1 day postoperatively, 7 days postoperatively, 6 months postoperatively, and 12 months postoperatively (P<0.05). The study group exhibited lower serum calcium levels than the control group 1 day postoperatively, 7 days postoperatively, 1 month postoperatively, and 6 months postoperatively (P<0.05). Additionally, the study group demonstrated lower serum phosphorus levels compared to the control group 1 day postoperatively, 7 days postoperatively, and 6 months postoperatively (P<0.05).

Conclusions: The application of DP in patients with CKD complicated by refractory secondary HPT holds definite clinical value.

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解剖式甲状旁腺切除术在慢性肾病合并难治性继发性甲状旁腺功能亢进患者中的应用价值。

目的：探讨解剖式甲状旁腺切除术（DP）治疗慢性肾病（CKD）合并难治性继发性甲状旁腺功能亢进（HPT）的临床价值。对象和方法：以CKD合并难治性继发HPT患者为研究对象。其中，42例接受DP治疗的患者作为研究组，42例接受常规甲状旁腺全切除术的患者作为对照组。结果：研究组平均手术时间和术后平均住院时间均低于对照组(p)。结论：DP在CKD合并难治性继发HPT患者中的应用具有明确的临床价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Endocrinologica-Bucharest 医学-内分泌学与代谢

CiteScore

1.30

自引率

20.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Acta Endocrinologica (Buc) is an international journal covering the fields of basic and clinical Endocrinology, Neuroendocrinology, Reproductive Medicine, Chronobiology, Human Ethology published quarterly Acta Endocrinologica (Buc) is the official international journal of the Romanian Society for Endocrinology. It continues the former Romanian Journal of Endocrinology