{"title":"α-Synuclein pathology in LRRK2 Parkinson disease","authors":"Ian Fyfe","doi":"10.1038/s41582-025-01113-7","DOIUrl":null,"url":null,"abstract":"Absence of Lewy body pathology in the form of Parkinson disease caused by mutations in the LRRK2 gene does not equate to a lack of α-synuclein pathology, two new studies have shown.","PeriodicalId":19085,"journal":{"name":"Nature Reviews Neurology","volume":"626 1","pages":""},"PeriodicalIF":28.2000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Neurology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41582-025-01113-7","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Absence of Lewy body pathology in the form of Parkinson disease caused by mutations in the LRRK2 gene does not equate to a lack of α-synuclein pathology, two new studies have shown.
期刊介绍:
Nature Reviews Neurology aims to be the premier source of reviews and commentaries for the scientific and clinical communities we serve. We want to provide an unparalleled service to authors, referees, and readers, and we work hard to maximize the usefulness and impact of each article. The journal publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians working in the field of neurology. Our broad scope ensures that the work we publish reaches the widest possible audience. Our articles are authoritative, accessible, and enhanced with clearly understandable figures, tables, and other display items. This page gives more detail about the aims and scope of the journal.