The Cheap Silk Sericin Displaying Chaperone-Like Activity to Stabilize Protein and Facilitate Protein Refolding

IF 9.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

CCS Chemistry Pub Date : 2025-06-14 DOI:10.31635/ccschem.025.202505877

Junyu Zhang, Xingqing Xiao, Donghui Zhang, Longqiang Liu, Wenjing Zhang, Qian Liang & Runhui Liu1State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 2002372Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Engineering Research Center for Biomedical Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 2002373Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 2151634Department of Chemistry, School of Chemistry and Chemical Engineering, Hainan University, Haikou City, Hainan Province 5702285Department of Orthopedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080

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Abstract

CCS Chemistry, Ahead of Print.
The inherent instability of proteins limits their application, which urgently calls for protein stabilizers to protect proteins from various environmental stresses. Inspired by late embryogenesis abundant proteins, we found that sericin exhibits chaperone-...

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来源期刊

CCS Chemistry Chemistry-General Chemistry

CiteScore

13.60

自引率

13.40%

发文量

475

审稿时长

10 weeks

期刊介绍： CCS Chemistry, the flagship publication of the Chinese Chemical Society, stands as a leading international chemistry journal based in China. With a commitment to global outreach in both contributions and readership, the journal operates on a fully Open Access model, eliminating subscription fees for contributing authors. Issued monthly, all articles are published online promptly upon reaching final publishable form. Additionally, authors have the option to expedite the posting process through Immediate Online Accepted Article posting, making a PDF of their accepted article available online upon journal acceptance.