A renal transplant recipient with a pulmonic valve mass.

IF 2.3 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Ilyse Darwish, Benoît de Varennes, Pierre Olivier Fiset, Sophie Camilleri-Broët, Vynka Lash, Marcelo Cantarovich, Todd C Lee, Cecilia T Costiniuk
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引用次数: 0

Abstract

A 43-year-old female with a renal transplant presented with fatigue, dyspnea, anemia, and thrombocytopenia. Chest CT revealed pulmonary nodules, and transthoracic echocardiography identified a large, multi-lobulated, multi-cystic mass attached to the pulmonic valve. Pathology demonstrated fungal hyphae, and bronchoalveolar lavage (BAL) fluid grew Aspergillus fumigatus, with a serum Aspergillus galactomannan (GM) antigen index of 1.95. The pulmonic valve was excised and a bioprosthetic valve was inserted. The patient was treated with voriconazole. Pulmonic valve Aspergillus endocarditis (AE) is a rare condition associated with high mortality. Given the rising number of transplant recipients, heightened clinical vigilance is warranted in this population.

肾移植受者肺动脉瓣肿块。
一例43岁女性肾移植患者表现为疲劳、呼吸困难、贫血和血小板减少。胸部CT显示肺结节,经胸超声心动图发现肺动脉瓣附着一个大的、多分叶的、多囊性肿块。病理证实有真菌菌丝,支气管肺泡灌洗液中有烟曲霉生长,血清半乳甘露聚糖曲霉抗原指数为1.95。切除肺动脉瓣,置入生物假体瓣膜。病人用伏立康唑治疗。肺动脉瓣曲霉菌性心内膜炎(AE)是一种罕见的疾病,死亡率高。鉴于移植受者人数的增加,在这一人群中提高临床警惕是有必要的。
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来源期刊
Cardiovascular Pathology
Cardiovascular Pathology 医学-病理学
CiteScore
7.50
自引率
2.70%
发文量
71
审稿时长
18 days
期刊介绍: Cardiovascular Pathology is a bimonthly journal that presents articles on topics covering the entire spectrum of cardiovascular disease. The Journal''s primary objective is to publish papers on disease-oriented morphology and pathogenesis from clinicians and scientists in the cardiovascular field. Subjects covered include cardiovascular biology, prosthetic devices, molecular biology and experimental models of cardiovascular disease.
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