Advancements in Targeted Therapy for Oral Cancer: A Mini Review.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY
Journal of pharmacy & bioallied sciences Pub Date : 2025-05-01 Epub Date: 2025-04-09 DOI:10.4103/jpbs.jpbs_1935_24
Sakshi G Ingole, Ashwini A Aher, Sunil N Thitame
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引用次数: 0

Abstract

Targeted therapy has become the latest revolution in the management of oral cancer by focusing on the molecular characteristic of the tumor to provide treatment with an accuracy that spares normal healthy tissue. This article discusses current advances in targeted medicine, with focusing on EGFR inhibitors, immune checkpoint inhibitors, and more biomarker-drug-directed therapies. Some of the important advances in enhancing the combination of these therapies with the conventional treatments including surgery, radiation, and chemotherapy are being described here. Furthermore, such features as tailoring medicine for patient needs in order to enhance therapeutic efficacy and counter drug resistance are pointed out as vision with a relatively bright prognosis for increasing survival rates as well as a quality of life of oral cancer patients.

口腔癌靶向治疗进展综述
靶向治疗已成为口腔癌管理的最新革命,通过关注肿瘤的分子特征,提供准确的治疗,以保护正常的健康组织。本文讨论了靶向药物的最新进展,重点是EGFR抑制剂、免疫检查点抑制剂和更多的生物标志物药物导向治疗。在加强这些疗法与传统疗法(包括手术、放疗和化疗)结合方面的一些重要进展将在此介绍。并指出因材施药,提高疗效,对抗耐药等特点,是提高口腔癌患者生存率和生活质量的一个预后比较光明的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.40
自引率
0.00%
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