Psychometric Properties of the European Organization for Research and Treatment of Cancer Head and Neck (EORTC QLQ H&N 43) Quality of Life Tool for Use in the Eastern India Population.
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引用次数: 0
Abstract
Head and neck cancer (HNC) and its treatment outcomes have a substantial impact on the quality of life of the patients. This study aimed to translate and psychometrically validate the European Organization for Research and Treatment of Cancer head and neck cancer-specific quality of life module, updated version (EORTC QLQ-H&N43) in Odia language for use in Eastern India. Forward-backward translation and pilot testing of the pre-final Odia version of the EORTC QLQ-H&N43 was done according to the EORTC quality of life group questionnaire translation guidelines. The psychometric properties were tested in a sample of 120 HNC patients attending a public tertiary hospital in Odisha. The patients filled in both the EORTC QLQ H&N 43 module and the EORTC QLQ C 30 questionnaire. Internal consistency was tested using Cronbach's alpha and the test-retest reliability using interclass correlation coefficients (ICC). The known group validity by disease stage was assessed and the convergent and discriminant validity were explored using the Spearman's correlation coefficient test. Exploratory factor analysis was performed to obtain information about the loading of the items and factor naming of the potential constructs was done. The Cronbach's Alpha of the scales ranged from 0.68 to 0.89 and was > 0.70 in 11 out of the 12 multi-item scales indicating good internal consistency. The ICC = 0.79 (95% confidence interval of 0.71-0.93) indicates a 'moderate' to 'good' test-retest reliability. The magnitude of the correlation of each item with its scale exceeded the correlation with another scale confirming item discriminant validity. All QLQ-H&N43 scales correlated negatively as predicted with all QLQ-C30 functioning scales. Significant known-group differences were observed between those in different stages of the disease. The factor analysis resulted in 3 different components namely oral/mouth-related symptoms, general functional disturbances, and psychosocial issues. The results suggest that the Odia version of EORTC QLQ-H&N43 is a reliable and valid tool for measuring the symptom burden of HNC patients in India. Future research on larger sample sizes can employ confirmatory factor analysis to further substantiate the findings of the present study.
Supplementary information: The online version contains supplementary material available at 10.1007/s12070-025-05549-7.
期刊介绍：
Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress.
IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc.
The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world.
The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members.
Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
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